Results 61 to 70 of about 112,452 (299)

Complex ventilation problems with no simple solution

open access: yesJournal of Mechanical Ventilation, 2022
Editorial on the article: Alveolar mechanics: A new concept in respiratory ...
Ross Freebairn
doaj   +1 more source

Review of hypoxaemia in the anaesthetized horse: predisposing factors, consequences and management [PDF]

open access: yes, 2017
Objectives: To discuss how hypoxaemia might be harmful and why the horse is particularly predisposed to developing it. To review the strategies that are used to manage hypoxaemia in anaesthetised horses, to describe how successful these strategies are
Auckburally, Adam, Nyman, Görel
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Features of respiratory support during laparoscopic correction of inguinal hernias in children

open access: yesVideosurgery and Other Miniinvasive Techniques, 2016
Introduction : The objectives were to study the changes in the mechanics of respiration in children undergoing surgery depending on the value of intra-abdominal pressure (IAP) during laparoscopic procedures, and to compare the effects of different ...
Volodymyr Mishchuk   +3 more
doaj   +1 more source

Extraction of reliable information from time-domain pressure and flow signals measured by means of forced oscillation techniques [PDF]

open access: yes, 2014
This paper aims to give a proof-of-concept for the possible application of the forced oscillation lung function test to assess the viscoelastic properties of the airways and tissue.
Baleanu, Dumitru   +3 more
core   +1 more source

A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]

open access: yes, 2012
Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J   +2 more
core   +2 more sources

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

Comparison of respiratory mechanics measurements in the volume cycled ventilation (VCV) and pressure controlled ventilation (PCV)

open access: yesFisioterapia em Movimento
Introduction Monitoring respiratory mechanics may provide important information for the intensivist, assisting in the early detection of pulmonary function changes of patients hospitalized in ICU.
Kelser de Souza Kock   +4 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

The Role of rescue therapies in the treatment of severe ARDS [PDF]

open access: yes, 2018
ARDS is characterized by a non-cardiogenic pulmonary edema with bilateral chest radiograph opacities and hypoxemia refractory to oxygen therapy. It is a common cause of admission to the ICU due to hypoxemic respiratory failure requiring mechanical ...
Alessandri, F, Pugliese, F, Ranieri, M.
core   +1 more source

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