Results 21 to 30 of about 136,655 (215)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Respiratory physiotherapy techniques used in patients with neurological disease

Listy klinicke logopedie, 2019
Breathing and its disorders are in the centre of interest of many medical and healthcare specialists. Paresis or loss of strength of skeletal muscles may often be observed in patients with neurological disease.
Daniela Botiková
doaj   +1 more source

Peripheral and respiratory muscle impairment during murine acute lung injury

Physiological Reports, 2022
Acute respiratory distress syndrome is associated with skeletal muscle compromise, which decreases survival and impairs functional capacity. A comparative analysis of peripheral and respiratory muscles' atrophy and dysfunction in acute lung injury (ALI ...
Martín Angulo, Agustina Vacca, Romina Rodríguez, María Noel Marin, Ana Laura Suárez, Gissel Jorge, Oscar Nosiglia, Victoria Cambón, Anaclara Ríos, Matías Iglesias, Mariana Seija, Carlos Escande, Javier Hurtado, Arturo Briva   +13 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Maximal dynamic inspiratory pressure: S-Index prediction values and diagnosis accuracy [PDF]

Jornal Brasileiro de Pneumologia
Objective: To establish reference values and prediction equations for the strength index (S-Index), in order to meet the growing demand for clinical application and diagnostic understanding of maximal dynamic inspiratory pressure.
Vitor Costa Souza, Maria Fernanda Lima Souza Saldanha, Eloara Vieira Machado Ferreira, Luiz Eduardo Nery, Priscila Cristina de Abreu Sperandio   +4 more
doaj   +1 more source

EFFECTIVENESS OF RESPIRATORY MUSCLE TRAINING FOR PULMONARY FUNCTION IN POST OPERATIVE PATIENTS

Rehman Journal of Health Sciences, 2023
Introduction: In cardiopulmonary respiratory muscles plays a vital role which is mostly affected in postoperative patients and leads to further respiratory complications.
Sarmad Saeed Khattak, Mishal Jamal, Marghalara Bangash, Laiba Nawaz, Khalid Khan, Sahibzada Saif Ullah Khalid   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Pulmonary Rehabilitation - PR

Albanian Journal of Trauma and Emergency Surgery, 2020
Chronic respiratory diseases are associated with severe, not only pulmonary, but also systemic damage such as dysfunction of peripheral muscles, dysfunction of respiratory muscles, nutritional disorders, cardiac injuries, skeletal disorders, sensory ...
Dh Argjiri, S Bala, F. Gradica, A Mezini, l. Agolli, V. Miha, V. Selmani, O. Nuredini, Y. Vakeflliu   +8 more
doaj   +1 more source