Human Metapneumovirus and Respiratory Syncytial Virus, Brazil [PDF]
We describe the epidemiologic and clinical characteristics of 111 children attending clinics and hospitals in Aracaju, northeast Brazil, with acute respiratory infections attributable to human metapneumovirus (HMPV), respiratory syncytial virus (RSV), or both in May and June 2002.
Julie Greensill+5 more
openaire +5 more sources
Innate Immune Evasion by Human Respiratory Syncytial Virus [PDF]
Respiratory syncytial virus (RSV) is the leading cause of severe respiratory infection in young children. Nearly all individuals become infected in their early childhood, and reinfections with RSV are common throughout life. Primary infection with RSV is usually involved in the symptom of bronchiolitis and pneumonia in the lower respiratory tract ...
Yan Ouyang+9 more
openaire +4 more sources
Human and bovine respiratory syncytial virus vaccine research and development [PDF]
Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely related viruses, which are the most important causative agents of respiratory tract infections of young children and calves, respectively.
Deplanche, Martine+2 more
core +7 more sources
Bacterial and Viral Coinfections with the Human Respiratory Syncytial Virus [PDF]
The human respiratory syncytial virus (hRSV) is one of the leading causes of acute lower respiratory tract infections in children under five years old. Notably, hRSV infections can give way to pneumonia and predispose to other respiratory complications later in life, such as asthma.
Gaspar A. Pacheco+4 more
openaire +5 more sources
The level and duration of RSV-specific maternal IgG in infants in Kilifi Kenya [PDF]
Background Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in infants. The rate of decay of RSV-specific maternal antibodies (RSV-matAb), the factors affecting cord blood levels, and the relationship between ...
Charles Sande+7 more
core +13 more sources
Human Respiratory Syncytial Virus: Infection and Pathology [PDF]
The human respiratory syncytial virus (hRSV) is by far the major cause of acute lower respiratory tract infections (ALRTIs) worldwide in infants and children younger than 2 years. The overwhelming number of hospitalizations due to hRSV-induced ALRTI each year is due, at least in part, to the lack of licensed vaccines against this virus.
Bohmwald Prieto, Karen+7 more
openaire +6 more sources
Respiratory Syncytial Virus and Human Bronchial Epithelium [PDF]
A suitable model for respiratory syncytial virus (RSV) infection has yet to be developed.To describe an in vitro model of human respiratory epithelium in primary cell culture linked with a computer microscope interface that allows evaluation and imaging of living RSV-infected respiratory epithelium.A descriptive, controlled study. Human bronchial cells
Debra A. Tristram+2 more
openaire +3 more sources
Transcriptional mapping of human respiratory syncytial virus [PDF]
A transcriptional map for human respiratory syncytial virus was determined by measuring the kinetics of viral gene inactivation in response to UV irradiation. Monolayer cell cultures of respiratory syncytial virus-infected HEp-2 cells were exposed to UV light, and residual viral RNA synthesis was monitored both by gel electrophoresis and by ...
Peter L. Collins+2 more
openaire +3 more sources
Incidence of viral respiratory infections in a prospective cohort of outpatient and hospitalized children aged ≤5 years and its associated cost in Buenos Aires, Argentina [PDF]
Background: Although information about the incidence of viral respiratory illnesses and their associated cost can help health officials explore the value of interventions, data are limited from middle-income countries.
Azziz Baumgartner, Eduardo+6 more
core +1 more source
A novel host factor for human respiratory syncytial virus [PDF]
Human respiratory syncytial virus (RSV) is the leading viral cause of severe lower respiratory disease in young children worldwide. As part of a genome-wide siRNA screen, we recently discovered that actin-related protein 2 (ARP2) is a host factor in the RSV replication cycle.
Peter L. Collins+2 more
openaire +4 more sources