Results 31 to 40 of about 93,278 (240)

N6 -Methyladenosine Negatively Regulates Human Respiratory Syncytial Virus Replication [PDF]

Frontiers in Cell and Developmental Biology, 2021
N6-methyladenosine (m6A) is the most abundant internal modification described in eukaryotic mRNA and several viral RNA including human respiratory syncytial virus (HRSV). Here, we evaluated the impact of m6A writers, erasers and readers on HRSV genomic RNA accumulation and inclusion bodies assembly during viral replication.
Fabian Figueroa, Alonso Vega-Gibson, Joseline Catrileo, Aracelly Gaete-Argel, Aracelly Gaete-Argel, Sebastian Riquelme-Barrios, Sebastian Riquelme-Barrios, Luis Antonio Alonso-Palomares, Luis Antonio Alonso-Palomares, Lorena I. Tapia, Lorena I. Tapia, Fernando Valiente-Echeverría, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Ricardo Soto-Rifo, Monica L. Acevedo   +15 more
openaire   +4 more sources

Conformational Isomerization Involving Conserved Proline Residues Modulates Oligomerization of the NS1 Interferon Response Inhibitor from the Syncytial Respiratory Virus [PDF]

, 2019
Interferon response suppression by the respiratory syncytial virus relies on two unique nonstructural proteins, NS1 and NS2, that interact with cellular partners through high-order complexes.
Alonso, Leonardo Gabriel, Aran, Martin, Borkosky, Silvina Susana, Conci, Julieta, de Oliveira, Guilherme A. P., de Prat Gay, Gonzalo, Esperante, Sebastian, Mohana Borges, Ronaldo, Pagani, Talita Duarte, Álvarez Paggi, Damián Jorge   +9 more
core   +1 more source

The Use of Aerosolized Ribavirin in Respiratory Syncytial Virus Lower Respiratory Tract Infections in Adult Immunocompromised Patients: A Systematic Review [PDF]

, 2019
Introduction: Respiratory syncytial virus (RSV)–associated lower respiratory tract infection (LRTI) is a concern in immunocompromised patients. Aerosolized ribavirin (RBV AER) is used for treatment of RSV LRTI; however, adverse events and rising drug ...
Avery, Lisa M., Hoffmann, Charles, Whalen, Karen M.   +2 more
core   +2 more sources

Contemporaneous data on the prevalence of Human Respiratory Syncytial Virus infection in people with acute respiratory tract infections in Africa (2000–2017)

Data in Brief, 2018
Availability of accurate data on the burden of the Human Respiratory Syncytial Virus (HRSV) can help to implement better strategies to curb this burden in Africa continent among people with acute respiratory tract infections (ARTI).
Jean Joel Bigna, Sebastien Kenmoe, Estelle Amandine Well, Fredy Brice N. Simo, Véronique B. Penlap, Astrid Vabret, Richard Njouom   +6 more
doaj   +1 more source

Respiratory viruses in mechanically ventilated patients: a pilot study

BMC Pulmonary Medicine, 2020
Background Respiratory virome is an integral part of the human microbiome and its characterization may contribute to a better understanding of the changes that arise in the disease and, consequently, influence the approach and treatment of patients with ...
Raquel Nazareth, Maria-Jesus Chasqueira, Maria-Lúcia Rodrigues, Carolina Paulino, Catarina Conceição, Lia Lêdo, Úrsula Segura, Madalena Santos, António Messias, Pedro Póvoa, Paulo Paixão   +10 more
doaj   +1 more source

Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections [PDF]

, 2017
Background: Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between infants with B.
Agricola, Eleonora, Buttinelli, Gabriele, Campagna, Ilaria, Carsetti, R., Concato, C., DI MATTIA, Greta, Fedele, Giorgio, Ferretti, Beatrice, Frassanito, Antonella, Gesualdo, Francesco, Gonfiantini, Michaela Veronika, Marcellini, Valentina, Midulla, Fabio, Nenna, Raffaella, Nicolai, Ambra, Pandolfi, Elisabetta, Pierangeli, Alessandra, Russo, Luisa, Schiavoni, I., Stefanelli, P., Tozzi, A. E., Vennarucci, Valentina Spuri, Villani, Alberto   +22 more
core   +1 more source

Identifying Cross-Utilization of RSV Vaccine Inventions across the Human and Veterinary Field

Pathogens, 2022
The respiratory syncytial virus (RSV) has two main variants with similar impact, a human and a bovine variant. The human respiratory syncytial virus (HRSV) is the most frequent cause of acute respiratory disease (pneumonia) in children, leading to ...
Marga Janse, Swasti D. Soekhradj, Rineke de Jong, Linda H. M. van de Burgwal   +3 more
doaj   +1 more source

The incidence and clinical burden of respiratory syncytial virus disease identified through hospital outpatient presentations in Kenyan children [PDF]

, 2012
There is little information that describe the burden of respiratory syncytial virus (RSV) associated disease in the tropical African outpatient setting. Methods We studied a systematic sample of children aged
Ann Bett, Benjamin J. Cowling, BG Williams, BJ Selwyn, CB Hall, D. James Nokes, DJ Nokes, DJ Nokes, DJ Nokes, EA Okiro, EA Okiro, EA Okiro, Emelda A. Okiro, F Freymuth, F Henderson, FE Moura, I Rudan, J Bryce, JAG Scott, K Mulholland, MK Mwaniki, MP Loscertales, MP Loscertales, MW Weber, MW Weber, MW Weber, Mwanajuma Ngama, PD Scott, PD Scott, PD Scott, R Ochola, RG Fisher, SA Madhi, SE Robertson, TW Mwangi, W Glezen   +35 more
core   +2 more sources

Human Respiratory Syncytial Virus Detected in Mountain Gorilla Respiratory Outbreaks [PDF]

EcoHealth, 2020
AbstractRespiratory illness (RI) accounts for a large proportion of mortalities in mountain gorillas (Gorilla beringei beringei), and fatal outbreaks, including disease caused by human metapneumovirus (HMPV) infections, have heightened concern about the risk of human pathogen transmission to this endangered species, which is not only critically ...
Mazet, Jonna A. K., Genovese, Brooke N., Harris, Laurie A., Cranfield, Michael, Noheri, Jean Bosco, Kinani, Jean Felix, Zimmerman, Dawn, Bahizi, Methode, Mudakikwa, Antoine, Goldstein, Tracey, Gilardi, Kirsten V. K.   +10 more
openaire   +2 more sources

Statistical Analysis of Common Respiratory Viruses Reveals the Binary of Virus-Virus Interaction

Microbiology Spectrum, 2023
Respiratory viruses may interfere with each other and affect the epidemic trend of the virus. However, the understanding of the interactions between respiratory viruses at the population level is still very limited.
Lulu Zhang, Yan Xiao, Zichun Xiang, Lan Chen, Ying Wang, Xinming Wang, Xiaojing Dong, Lili Ren, Jianwei Wang   +8 more
doaj   +1 more source