Results 11 to 20 of about 152,217 (292)

Possible respiratory syncytial virus infection presenting as diffuse alveolar hemorrhage in an elderly treated with systemic corticosteroid: A case report

Respiratory Medicine Case Reports, 2021
Introduction: Respiratory syncytial virus infection is gaining interest in the elderly due to its growing morbidity and mortality. We present a Case of respiratory syncytial virus infection presenting as diffuse alveolar hemorrhage that was highly ...
Kyung Hun Nam, MD MPH, Junho Kang, MD, Younsuck Koh, MD PhD FCCM   +2 more
doaj   +1 more source

EDP-938, a Respiratory Syncytial Virus Inhibitor, in a Human Virus Challenge.

New England Journal of Medicine, 2022
BACKGROUND Respiratory syncytial virus (RSV) infection causes substantial morbidity and mortality among infants, older adults, and immunocompromised adults.
A. Ahmad, Kingsley Eze, N. Noulin, V. Horváthová, Bryan Murray, M. Baillet, Laura Grey, J. Mori, N. Adda   +8 more
semanticscholar   +1 more source

Respiratory virus infections in hospitalized and non-hospitalized children: determinants of severe course of the disease

Journal of Infection in Developing Countries, 2022
Introduction: Viral respiratory disease constitutes a great burden worldwide mainly among children. Objective: One pursued to compare disease characteristics of children who required hospitalization from those who did not require hospitalization due to ...
Lourenço Faria Costa, Hélio Lopes da Silveira, Divina Aparecida Oliveira Queiróz, Orlando Cesar Mantese, Jonny Yokosawa   +4 more
doaj   +1 more source

Genetic diversity and molecular evolution of human respiratory syncytial virus A and B

Scientific Reports, 2021
Human respiratory syncytial viruses (RSVs) are classified into two major groups (A and B) based on antigenic differences in the G glycoprotein.
Jie-mei Yu, Yuan-Hui Fu, Xiang-Lei Peng, Yanpeng Zheng, Jinsheng He   +4 more
semanticscholar   +1 more source

Thapsigargin Is a Broad-Spectrum Inhibitor of Major Human Respiratory Viruses: Coronavirus, Respiratory Syncytial Virus and Influenza A Virus

Viruses, 2021
The long-term control strategy of SARS-CoV-2 and other major respiratory viruses needs to include antivirals to treat acute infections, in addition to the judicious use of effective vaccines.
Sarah Al-Beltagi, C. Preda, Leah V. Goulding, Joe James, Juan Pu, P. Skinner, Zhimin Jiang, Belinda Wang, Jiayun Yang, A. Banyard, K. Mellits, P. Gershkovich, C. Hayes, J. Nguyen-Van-Tam, I. Brown, Jinhua Liu, Kin-Chow Chang   +16 more
semanticscholar   +1 more source

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein [PDF]

, 2014
Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic (SH) protein ...
Bert Schepens, Brian Gilbert, Cherrie AH, Connors M, Glezen WP, Kenny Roose, Koen Sedeyn, Liesbeth Vande Ginste, Lieselot Houspie, Marc Van Ranst, Michael Schotsaert, Mills JT, Nicholas JA, Nico Rooijen, Olmsted RA, Pedro Piedra, Sarah De Baets, Ventre K, Walter Fiers, Whitehead SS, Xavier Saelens   +20 more
core   +11 more sources

Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus

Nature Communications, 2021
Human respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection in young children globally, but little is known about within-host RSV diversity.
Gu-Lung Lin, S. Drysdale, M. Snape, D. O’Connor, Anthony Brown, G. Macintyre-Cockett, E. Mellado-Gomez, M. de Cesare, D. Bonsall, M. Ansari, Deniz Öner, J. Aerssens, Christopher Butler, L. Bont, P. Openshaw, F. Martinón-Torres, H. Nair, R. Bowden, Harry Steve Debby Philippe Joanne Elizabeth Joseph Ryan Campbell Cunningham Bogaert Beutels Wildenbeest Cl, H. Campbell, S. Cunningham, D. Bogaert, P. Beutels, J. Wildenbeest, E. Clutterbuck, J. McGinley, R. Thwaites, D. Wiseman, A. Gómez-Carballa, C. Rodríguez-Tenreiro, I. Rivero-Calle, Ana Dacosta-Urbieta, T. Heikkinen, A. Meijer, T. Fischer, M. van den Berge, C. Giaquinto, M. Abram, P. Dormitzer, S. Stoszek, Scott Gallichan, B. Rosen, Eva Molero, Núria Machín, Martina Spadetto, T. Golubchik, A. Pollard   +46 more
semanticscholar   +1 more source

Bovine respiratory syncytial virus protects cotton rats against human respiratory syncytial virus infection [PDF]

Journal of Virology, 1993
Human respiratory syncytial virus (HRSV) is the most frequent cause of severe respiratory infections in infancy. No vaccine against this virus has yet been protective, and antiviral drugs have been of limited utility. Using the cotton rat model of HRSV infection, we examined bovine respiratory syncytial virus (BRSV), a cause of acute respiratory ...
F M, Piazza, S A, Johnson, M E, Darnell, D D, Porter, V G, Hemming, G A, Prince   +5 more
openaire   +2 more sources

Comparative assessment of reported symptoms of influenza, respiratory syncytial virus, and human metapneumovirus infection during hospitalization and post‐discharge assessed by Respiratory Intensity and Impact Questionnaire

Influenza and Other Respiratory Viruses, 2021
The hospitalized acute respiratory tract infection (HARTI) study used the Respiratory Intensity and Impact Questionnaire (RiiQ™) Symptom Scale, derived from FluiiQ™, to assess and compare the burden of respiratory infection symptoms for patients with ...
A. Falsey, E. Walsh, R. Osborne, Yannick Vandendijck, Xiaohui Ren, J. Witek, Diye Kang, Eric K. H. Chan, J. Scott, G. Ispas   +9 more
semanticscholar   +1 more source

Transcriptional mapping of human respiratory syncytial virus [PDF]

Journal of Virology, 1984
A transcriptional map for human respiratory syncytial virus was determined by measuring the kinetics of viral gene inactivation in response to UV irradiation. Monolayer cell cultures of respiratory syncytial virus-infected HEp-2 cells were exposed to UV light, and residual viral RNA synthesis was monitored both by gel electrophoresis and by ...
L E, Dickens, P L, Collins, G W, Wertz
openaire   +3 more sources