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Purification of human respiratory syncytial virus fusion glycoprotein
Protein Expression and Purification, 2012Human respiratory syncytial virus (RSV) fusion glycoprotein (F) elicits neutralizing antibodies to RSV and has therefore attracted much attention as a suitable candidate antigen in the development of gene-based vaccines against RSV infections. However, a major obstacle in vaccine development has been the problem of antigen purification. To address this
Yanpeng, Zheng +5 more
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Respiratory syncytial virus interaction with human airway epithelium
Trends in Microbiology, 2013Although respiratory syncytial virus (RSV) is a major human respiratory pathogen, our knowledge of how it causes disease in humans is limited. Airway epithelial cells are the primary targets of RSV infection in vivo, so the generation and exploitation of RSV infection models based on morphologically and physiologically authentic well-differentiated ...
Villenave, Remi +2 more
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Human respiratory syncytial virus and Th1 chemokines.
La Clinica terapeutica, 2015The importance of the Type-1 helper (Th1) chemokines in RSV (respiratory syncytial virus) infection has been shown by several studies, in animal models, and in humans. The production of Th1 chemokines within the lower respiratory tract has been shown in patients with RSV bronchiolitis, particularly chemokine (C-X-C motif) ligand (CXCL)10/interferon-γ ...
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Immunity to human and bovine respiratory syncytial virus
Archives of Virology, 1990Human and bovine respiratory syncytial viruses resemble each other closely. During annual winter outbreaks, they cause similar respiratory tract disease in infants and calves. The disease is most severe in children and calves between 1 and 3 months old, when maternal antibodies against the virus are usually present.
T G, Kimman, F, Westenbrink
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Respiratory Syncytial Virus and Human Metapneumovirus
2015Respiratory syncytial virus (RSV) is one of the most vulnerable pathogens to environmental changes. RSV is the major cause of lower respiratory tract illnesses such as bronchiolitis, tracheobronchitis, and pneumonia among infants and young children worldwide.
N. Esther Babady, Yi-Wei Tang
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Molecular epidemiology of human respiratory syncytial virus
Seminars in Virology, 1995Abstract Human respiratory syncytial virus (HuRSV) is the majorviral cause of severe lower respiratory tract disease in babies and infants with epidemics occurring annually in the winter in temperate climates. Analysis of the antigenic and genetic variability of HuRSV isolates has shown that there are two groups of the virus and that each group can ...
Patricia A. Cane, Craig R. Pringle
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American Association of Bovine Practitioners Conference Proceedings, 2010
Bovine respiratory syncytial virus (BRSV) causes a severe interstitial pneumonia primarily in calves from birth to 12 months of age, and is a significant component of the bovine respiratory disease complex. Current detection of BRSV is performed by laboratory-based methods including direct and indirect immunofluorence, real time-polymerase chain ...
Barbu, N. +4 more
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Bovine respiratory syncytial virus (BRSV) causes a severe interstitial pneumonia primarily in calves from birth to 12 months of age, and is a significant component of the bovine respiratory disease complex. Current detection of BRSV is performed by laboratory-based methods including direct and indirect immunofluorence, real time-polymerase chain ...
Barbu, N. +4 more
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[Humanized respiratory syncytial virus monoclonal antibody].
Nihon rinsho. Japanese journal of clinical medicine, 2002Respiratory syncytial virus remains a significant cause of severe lower respiratory tract disease in children. The risk of serious RSV illness is highest among children with prematurity, chronic lung disease and congenital heart disease. No effective vaccine and anti-viral agents have been obtained even now.
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Respiratory syncytial virus infection and novel interventions
Nature Reviews Microbiology, 2023Louis Bont, Annefleur C Langedijk
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