In vivo evidence for quasispecies distributions in the bovine respiratory syncytial virus genome [PDF]
, 2007 We analyzed the genetic evolution of bovine respiratory syncytial virus (BRSV) isolate W2-00131, from its isolation in bovine turbinate (BT) cells to its inoculation in calves.
Bonnet, Marion +5 more
core +1 more source
Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases [PDF]
, 2004 For two centuries, vaccination has been the dominating approach to develop prophylaxis against viral infections through immunological prevention. However, vaccines are not always possible to make, are ineffective for many viral infections, and also carry
Fang, Fang, Le Calvez, Hervé, Yu, Mang
core +3 more sources
The Human Immune Response to Respiratory Syncytial Virus Infection [PDF]
Clinical Microbiology Reviews, 2017 SUMMARYRespiratory syncytial virus (RSV) is an important etiological agent of respiratory infections, particularly in children. Much information regarding the immune response to RSV comes from animal models andin vitrostudies. Here, we provide a comprehensive description of the human immune response to RSV infection, based on a systematic literature ...
Clark D. Russell +3 more
openaire +4 more sources
Journal of the Formosan Medical Association, 2014 To investigate the prevalence of common viruses and Mycoplasma pneumoniae (MP) in hospitalized infants with acute bronchiolitis and study the relationship between bronchiolitis and meteorological conditions.
Zheng-Rong Chen +6 more
doaj +1 more source
PLoS ONE, 2021 BackgroundViruses are responsible for a large proportion of acute respiratory tract infections (ARTIs). Human influenza, parainfluenza, respiratory-syncytial-virus, and adenoviruses are among the leading cause of ARTIs.
Therese Umuhoza +5 more
doaj +1 more source
Genetic relatedness of infecting and reinfecting respiratory syncytial virus strains identified in a birth cohort from rural Kenya [PDF]
, 2012 Background: Respiratory syncytial virus (RSV) reinfects individuals repeatedly. The extent to which this is a consequence of RSV antigenic diversity is unclear.
Alexander G. Mwihuri +50 more
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Genomics of Human Respiratory Syncytial Virus Vaccine Attenuation [PDF]
, 2019 ABSTRACTThe human orthopneumovirus (HRSV) is a major cause of lower respiratory tract infection in children worldwide. Despite decades of efforts, no vaccine is available. In this work, we report mutations that are frequent in vaccine candidates and rare in wild-type genomes, taking into account all the publicly available HRSV sequence data.
Thomas Junier +6 more
openaire +2 more sources
Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein [PDF]
, 2014 Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic (SH) protein ...
Bert Schepens +20 more
core +3 more sources
Bovine respiratory syncytial virus protects cotton rats against human respiratory syncytial virus infection [PDF]
Journal of Virology, 1993 Human respiratory syncytial virus (HRSV) is the most frequent cause of severe respiratory infections in infancy. No vaccine against this virus has yet been protective, and antiviral drugs have been of limited utility. Using the cotton rat model of HRSV infection, we examined bovine respiratory syncytial virus (BRSV), a cause of acute respiratory ...
S. A. Johnson +5 more
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Respiratory syncytial virus: Clinical and epidemiological pattern in pediatric patients admitted to a children’s hospital between 2000 and 2013 [PDF]
, 2014 INTRODUCTION: Respiratory syncytial virus (RSV) is the major causative organism associated with acute lower respiratory tract infections in children.The objective of this study was to describe the clinical and epidemiological pattern of RSV and identify ...
Bakir, Julia +8 more
core +1 more source