Results 51 to 60 of about 79,643 (236)

Model evaluation of target product profiles of an infant vaccine against respiratory syncytial virus (RSV) in a developed country setting [PDF]

, 2020
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract disease in children worldwide and is a significant cause of hospital admissions in young children in England.
Kinyanjui, Timothy, Nokes, D. James, Pan-Ngum, Wirichada, Saralamba, Sompob, Taylor, Sylvia, White, Lisa J.   +5 more
core   +1 more source

Activation of Human Eosinophils In Vitro by Respiratory Syncytial Virus [PDF]

Pediatric Research, 1992
To determine the nature of the interaction between viruses and eosinophils, normodense eosinophils were separated from the blood of healthy volunteers and incubated in vitro with respiratory syncytial virus (RSV). After incubation for 2 h with the virus, 29.5 +/- 15.8% of the eosinophils demonstrated specific binding of the virus to the cell membrane ...
Jan L.L. Kimpen, Pearay L. Ogra, Robert C. Welliver, Roberto P. Garofalo   +3 more
openaire   +3 more sources

Bronchiolitis. Analysis of 10 consecutive epidemic seasons [PDF]

, 2016
Bronchiolitis is the leading cause of hospitalization in infants under 12 months. Our aims were to analyze epidemiological characteristics of infants with bronchiolitis over 10 consecutive seasons and to evaluate whether there are any clinical ...
Antonelli, Guido, Cangiano, Giulia, Capocaccia, Paolo, Evangelisti, Melania, Frassanito, Antonella, Midulla, Fabio, Moretti, Corrado, Nenna, Raffaella, Nicolai, Ambra, Papoff, Paola, Petrarca, Laura, Pierangeli, Alessandra, Scagnolari, Carolina   +12 more
core   +1 more source

Human Metapneumovirus and Severity of Respiratory Syncytial Virus Disease

Emerging Infectious Diseases, 2004
We screened 23 children with severe respiratory syncytial virus (RSV) disease and 23 children with mild RSV disease for human metapneumovirus (HMPV). Although HMPV was circulating in Connecticut, none of the 46 RSV-infected patients tested positive for HMPV. In our study population, HMPV did not contribute to the severity of RSV disease.
James Dziura, Isaac Lazar, Marie L. Landry, David Ferguson, Jeffrey S. Kahn, Carla Weibel   +5 more
openaire   +3 more sources

Optimal control of a fractional order epidemic model with application to human respiratory syncytial virus infection [PDF]

, 2018
A human respiratory syncytial virus surveillance system was implemented in Florida in 1999, to support clinical decision-making for prophylaxis of premature newborns. Recently, a local periodic SEIRS mathematical model was proposed in [Stat. Optim.
Rosa, Silverio, Torres, Delfim F. M.
core   +2 more sources

Human respiratory syncytial virus and coronavirus rates in Iranian elderly patients more than 60 years old with acute respiratory symptoms

Advanced Biomedical Research, 2023
Background: Scientists have believed that a number of risk factors, especially viral infectious agents, can be related to respiratory diseases. Due to the pandemics in 2019, Human Respiratory Syncytial Virus and Coronavirus have attracted the attention ...
Shaian Tavakolian, Hossein Goudarzi, Ilad Alavi Darazam, Ebrahim Faghihloo   +3 more
doaj   +1 more source

Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery

Advanced Healthcare Materials, EarlyView.
Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou, Johanna Simon, Moritz Beck‐Broichsitter, Gary Davidson, Pavel A. Levkin   +4 more
wiley   +1 more source

Bovine respiratory syncytial virus seroprevalence and risk factors in feedlot cattle from Córdoba and Santa Fe, Argentina [PDF]

, 2017
El virus respiratorio sincicial bovino (BRSV) es uno de los agentes causantes de enfermedad respiratoria bovina a nivel mundial, conduciendo a importantes pérdidas económicas.
Aznar, Natalia, Dus Santos, María José, Ferella, Alejandra, Margineda, Carlos, Mozgovoj, Marina Valeria, Pérez Aguirreburualde, María Sol, Sammarruco, Ayelen   +6 more
core   +1 more source

Two Distinct Subtypes of Human Respiratory Syncytial Virus

Journal of General Virology, 1985
Antigenic variation of human respiratory syncytial (RS) virus strains was analysed using a collection of nine, six, six, nine and one monoclonal antibodies respectively directed against the large glycoprotein (G), fusion protein (F), matrix protein (M), nucleoprotein (NP) and phosphoprotein (P) components of the Long strain of RS virus.
Maurice A. Mufson, Björg Rafnar, Claes Örvell, Erling Norrby   +3 more
openaire   +3 more sources

Contribution of IDO to human respiratory syncytial virus infection [PDF]

Journal of Leukocyte Biology, 2019
Abstract IDO is an enzyme that participates in the degradation of tryptophan (Trp), which is an essential amino acid necessary for vital cellular processes. The degradation of Trp and the metabolites generated by the enzymatic activity of IDO can have immunomodulating effects, notably over T cells, which are particularly sensitive to the
Benavente, Felipe M., Soto Ramírez, Jorge Andrés, Pizarro Ortega, Magdalena S., Bohmwald Prieto, Karen, González, Pablo A., Bueno Ramírez, Susan, Kalergis Parra, Alexis Mikes   +6 more
openaire   +4 more sources