Results 11 to 20 of about 1,288,949 (271)

Cetylpyridinium chloride and chlorhexidine show antiviral activity against Influenza A virus and Respiratory Syncytial virus in vitro.

PLoS ONE
BackgroundThe oral cavity is the site of entry and replication for many respiratory viruses. Furthermore, it is the source of droplets and aerosols that facilitate viral transmission.
Marina Rius-Salvador, Maria Jesús García-Múrria, Luciana Rusu, Manuel Bañó-Polo, Rubén León, Ron Geller, Ismael Mingarro, Luis Martinez-Gil   +7 more
doaj   +2 more sources

Cholesterol is required for stability and infectivity of influenza A and respiratory syncytial viruses. [PDF]

Virology, 2017
Cholesterol-rich lipid raft microdomains in the plasma membrane are considered to play a major role in the enveloped virus lifecycle. However, the functional role of cholesterol in assembly, infectivity and stability of respiratory RNA viruses is not fully understood. We previously reported that depletion of cellular cholesterol by cholesterol-reducing
Bajimaya S, Frankl T, Hayashi T, Takimoto T.   +3 more
europepmc   +3 more sources

Natural infection of pangolins with human respiratory syncytial viruses

Current Biology, 2022
Respiratory syncytial virus (RSV) is an enveloped non-segmented negative sense RNA virus that belongs to Orthopneumovirus genus of the Pneumoviridae family in the order Mononegavirales. The virus is the leading cause of severe respiratory disease in children under two years of age and is responsible for substantial disease burden in infants and elder ...
Run-Ze, Ye, Teng-Cheng, Que, Luo-Yuan, Xia, Xiao-Ming, Cui, Ya-Wei, Zhang, Jia-Fu, Jiang, Qi-Hui, Wang, Qian, Wang, Mei-Hong, He, Lian-Feng, Li, Wenqiang, Shi, Li-Feng, Du, Yong-Jie, Wei, Hang, Fan, Yu-Qiong, Wu, Jin-Yue, Liu, Jia-Jing, Zheng, Yu-Sheng, Pan, Wei, Wei, Yan-Ling, Hu, Wu-Chun, Cao, Na, Jia   +21 more
openaire   +2 more sources

In Vivo Selection of Respiratory Syncytial Viruses Resistant to Palivizumab [PDF]

Journal of Virology, 2005
ABSTRACT Palivizumab (PZ) is the only monoclonal antibody currently available for use in humans against an infectious disease. PZ is administered prophylactically for respiratory syncytial virus (RSV) infections. RSV selected in cell culture for growth in the presence of PZ develops F gene mutations and can be resistant to PZ prophylaxis in ...
Xiaodong, Zhao, Wayne M, Sullender
openaire   +2 more sources

Comprehensive Performance Verification of the Mindray MN2880 System in Detecting Respiratory Virus Nucleic Acids. [PDF]

J Clin Lab Anal
This study verified the analytical performance of the fully automated Mindray MN2880 system for the simultaneous detection of SARS‐CoV‐2, influenza A/B viruses, and RSV in 2852 oropharyngeal swab specimens, following CNAS‐GL039:2019, CNAS‐GL037:2019, and ISO 15189:2022 guidelines.
Chen J, Zeng L, Huang H, Chen P.
europepmc   +2 more sources

Identification of group B respiratory syncytial viruses that lack the 60-nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya [PDF]

, 2013
Respiratory syncytial virus BA genotype has reportedly replaced other group B genotypes worldwide. We report the observation of three group B viruses, all identical in G sequence but lacking the BA duplication, at a coastal district hospital in Kenya in ...
Agoti, Charles N., Medley, Graham, Cane, Patricia, Nokes, D. James, Gitahi, Caroline W.   +4 more
core   +1 more source

In vivo evidence for quasispecies distributions in the bovine respiratory syncytial virus genome [PDF]

, 2007
We analyzed the genetic evolution of bovine respiratory syncytial virus (BRSV) isolate W2-00131, from its isolation in bovine turbinate (BT) cells to its inoculation in calves.
Mirandette, Carole, Schelcher, François, Bonnet, Marion, Meyer, Gilles, Deplanche, Martine, Lemaire, Mylène   +5 more
core   +1 more source

1409. Genomic Variation Among Respiratory Syncytial Viruses [PDF]

Open Forum Infect Dis, 2020
Abstract Background Respiratory Syncytial Virus (RSV) can be easily classified into two subtypes (A and B) based on the nucleic acid sequence of their genome. Phylogenic approaches have shown that within both subtypes separate lineages of viruses exist and new lineages continue to emerge.
Anderson C, Zhang Y, Corbett A, Chu C, Wang L, Qiu X, McCall M, Topham D, Mariani T, Walsh E, Scheuermann R, Caserta M.   +11 more
europepmc   +3 more sources

Genetic Variation and Disease Severity of Respiratory Syncytial Viruses [PDF]

, 2022
Abstract Respiratory Syncytial Virus (RSV) disease in newborns ranges from mild symptoms to severe disease requiring hospitalization. RSV is classified into two subtypes (RSVA and RSVB) based on antigenic and genetic differences. The role these genomic variations play in disease severity remains unknown.
Christopher S. Anderson, Yun Zhang, Anthony Corbett, Chinyi Chu, Alexander Grier, Lu Wang, Xing Qiu, Mathew Mccall, David J. Topham, Edward E. Walsh, Thomas J. Mariani, Richard Scheuermann, Mary T. Caserta   +12 more
openaire   +1 more source

Incidence and risk factors for respiratory syncytial virus and human metapneumovirus infections among children in the remote highlands of Peru [PDF]

, 2015
The disease burden and risk factors for respiratory syncytial virus (RSV) and human metapneumovirus (MPV) infections among children living in remote, rural areas remain unclear.; We conducted a prospective, household-based cohort study of children aged ...
Gil, Ana I., Philip J Budge, Kathryn M. Edwards (534416), Verastegui, Hector, Yuwei Zhu, Hector Verastegui, Grijalva, Carlos G, Carlos G. Grijalva, Grijalva, Carlos G., Stella Hartinger, Stella Hartinger (759804), Gil, Ana I, Marie R Griffin, Griffin, Marie R., Wu, Andrew, Lanata, Claudio F., Marie R. Griffin (209725), Marie R. Griffin, Monika Johnson, Ana I. Gil, Philip J. Budge (389401), Williams, John, Andrew Wu, Carlos G. Grijalva (236548), John Williams (32544), Zhu, Yuwei, Claudio F Lanata, Hector Verastegui (534417), Kathryn M Edwards, Andrew Wu (90389), Edwards, Kathryn M, John Williams, Yuwei Zhu (236550), Budge, Philip J, Johnson, Monika, Hartinger, Stella, Ana I. Gil (534420), Lanata, Claudio F, Ana I Gil, Claudio F. Lanata, Edwards, Kathryn M., Philip J. Budge, Griffin, Marie R, Carlos G Grijalva, Andrew Wu, Kathryn M. Edwards, Claudio F. Lanata (454212), Monika Johnson (12861), Budge, Philip J., Griffin Marie R., Grijalva Carlos G., Johnson Monika, Hartinger Stella, Lanata Claudio F., Zhu Yuwei, Verastegui Hector, Budge Philip J., Williams John, Wu Andrew, Edwards Kathryn M., Gil Ana I.   +60 more
core   +2 more sources