Angewandte Chemie, EarlyView.A new exponential RCA (E‐RCA) system was developed and coupled to a toehold system for release of a bridging DNA, allowing for lateral flow detection. The E‐RCA method uses a secondary primer (P2) that binds RCA products (RCAP) to generate extended P2 products that can re‐prime a partially self‐complementary circular template, generating a complete ...
Amal Mathai +3 more
wiley +2 more sources
A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]
, 2011 Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn +11 more
core +1 more source
Respiratory viruses in mechanically ventilated patients: a pilot study
BMC Pulmonary Medicine, 2020 Background Respiratory virome is an integral part of the human microbiome and its characterization may contribute to a better understanding of the changes that arise in the disease and, consequently, influence the approach and treatment of patients with ...
Raquel Nazareth +10 more
doaj +1 more source
The Range of Application of Domestic Antiviral Drug in Рediatrics
Детские инфекции (Москва), 2015 The article presents the results of studies of the effectiveness and safety of domestic antiviral drug Аrbidol in children. Arbidol demonstrated antiviral activity not only against influenza viruses, and other respiratory viruses (respiratory syncytial ...
O. V. Shamsheva, O. V. Molochkova
doaj +1 more source
The incidence and clinical burden of respiratory syncytial virus disease identified through hospital outpatient presentations in Kenyan children [PDF]
, 2012 There is little information that describe the burden of respiratory syncytial virus (RSV) associated disease in the tropical African outpatient setting. Methods We studied a systematic sample of children aged
Bett, Ann +11 more
core +1 more source
Risk factors for respiratory syncytial virus bronchiolitis hospital admission in New Zealand. [PDF]
, 2008 This study assessed risk factors for respiratory syncytial virus (RSV) hospitalization and disease severity in Wellington, New Zealand. During the southern hemisphere winter months of 2003--2005, 230 infants aged < 24 months hospitalized with ...
Rich, F. J. +21 more
core +1 more source
International Journal of Infectious Diseases, 2021 Objectives: The aim of this study was to determine the prevalence of respiratory virus infections, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), during the winter period December 2019 to March 2020, via a tertiary care hospital ...
Adriana Calderaro +12 more
doaj +1 more source
Statistical Analysis of Common Respiratory Viruses Reveals the Binary of Virus-Virus Interaction
Microbiology Spectrum, 2023 Respiratory viruses may interfere with each other and affect the epidemic trend of the virus. However, the understanding of the interactions between respiratory viruses at the population level is still very limited.
Lulu Zhang +8 more
doaj +1 more source
Aetiological role of viral and bacterial infections in acute adult lower respiratory tract infection (LRTI) in primary care [PDF]
, 2005 Background: Lower respiratory tract infections (LRTI) are a common reason for consulting general practitioners (GPs). In most cases the aetiology is unknown, yet most result in an antibiotic prescription.
McHugh, TD +26 more
core +1 more source
NOVA, 2016 Background. Multiplex real time PCR is increasingly used to diagnose respiratory viruses and has shown to be superior to traditional methods, such as culture and antigen detection. Objective.
Hernán Vargas +7 more
doaj +1 more source