A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]
Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Dubuquoy, Catherine, C. +36 more
core +1 more source
Genetics, recombination and clinical features of human rhinovirus species C (HRV-C) infections; interactions of HRV-C with other respiratory viruses [PDF]
To estimate the frequency, molecular epidemiological and clinical associations of infection with the newly described species C variants of human rhinoviruses (HRV), 3243 diagnostic respiratory samples referred for diagnostic testing in Edinburgh were ...
Anne Wisdom +14 more
core +2 more sources
Detection of minority variants within bovine respiratory syncytial virus populations using oligonucleotide-based microarrays [PDF]
Microarray technology, originally developed for highly parallel examination of gene expression is regarded as a potential tool in prognosis and diagnosis.
Leberre, Véronique +5 more
core +1 more source
Multiplex PCR for Typing and Subtyping Influenza and Respiratory Syncytial Viruses [PDF]
ABSTRACT A multiplex reverse transcription (RT)-PCR method that has been developed is capable of detecting and subtyping influenza A (H1N1 and H3N2) and B viruses as well as respiratory syncytial virus (RSV) types A and B in respiratory clinical samples taken as part of a national community-based surveillance program of influenza-like illness
J, Stockton +4 more
openaire +2 more sources
Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses. [PDF]
Morbidity and mortality resulting from influenza-like disease are a threat, especially for older adults. To improve case management, next-generation broad-spectrum antiviral therapeutics that are efficacious against major drivers of influenza-like ...
Yoon JJ +20 more
europepmc +2 more sources
A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]
Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn +11 more
core +1 more source
The natural history of respiratory syncytial virus in a birth cohort : the influence of age and previous infection on reinfection and disease [PDF]
This study aimed to quantify the effect of age, time since last infection, and infection history on the rate of respiratory syncytial virus infection and the effect of age and infection history on the risk of respiratory syncytial virus disease.
Bottomley, C +15 more
core +1 more source
Respiratory viruses in mechanically ventilated patients: a pilot study
Background Respiratory virome is an integral part of the human microbiome and its characterization may contribute to a better understanding of the changes that arise in the disease and, consequently, influence the approach and treatment of patients with ...
Raquel Nazareth +10 more
doaj +1 more source
Aetiological role of viral and bacterial infections in acute adult lower respiratory tract infection (LRTI) in primary care [PDF]
Background: Lower respiratory tract infections (LRTI) are a common reason for consulting general practitioners (GPs). In most cases the aetiology is unknown, yet most result in an antibiotic prescription.
McHugh, TD +27 more
core +1 more source
Influence of age, severity of infection, and co-infection on the duration of respiratory syncytial virus (RSV) shedding [PDF]
RSV is the most important viral cause of pneumonia and bronchiolitis in children worldwide and has been associated with significant disease burden. With the renewed interest in RSV vaccines, we provide realistic estimates on duration, and influencing ...
Agoti, Charles N. +23 more
core +1 more source

