Results 121 to 130 of about 546,892 (350)

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source

Outpatient Treatment of Lower Respiratory Tract Infections in Children with Tracheostomy [PDF]

, 2020
Parevi Majmudar, Don B. Sanders, Andrew L. Beardsley, James E. Slaven, A. Ioana Cristea   +4 more
openalex   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Palivizumab for the Prophylaxis of Respiratory Syncytial Virus Disease: Expert Opinion and Recommendations for the Gulf Cooperation Council Region

Oman Medical Journal
Respiratory syncytial virus (RSV) infection poses a significant health threat to infants and young children. Considering the substantial burden in Gulf Cooperation Council (GCC) countries, prevention of RSV remains a major public health priority ...
Adel S. Alharbi, Abdul Rahman Alnemri, Ahmed Abushahin, Entesar Alhammadi, Huda Sulaiman Mohammed AlDhanhani, Laila Obaid , Mahmoud Saleh ElHalik, Mariam Kh Ayed   +7 more
doaj   +1 more source

ADENOVIRUS: EPIDEMIOLOGY, SPREAD OF NOVEL SEROTYPES AND IN ROLE WITH RESPIRATORY TRACT INFECTIONS

, 2023
Annesha Das, Himadri Mondal, Shilpi Kundu, Agilus Diagnostics, Ps Srijan Tech, Kolkata- 700091., Shilpi Kundu, Agilus Diagnostics, Ps Srijan Tech, Kolkata- 700091.   +5 more
openalex   +1 more source

Assessing the Clinical and Economic Benefits of Implementing Point-of-care C-Reactive Protein Test to Manage Respiratory Tract Infections: Insights From Clinician Interviews in Four European Countries [PDF]

, 2023
Enyal Lani, Matthew Z. Wilson, Krishnan Puri Sudhir, Anne Meiwald, Katy Turner, Charlotte Hamlyn-Williams, Elisabeth J Adams   +6 more
openalex   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Respiratory tract infections and its preventive measures among hajj pilgrims, 2010: A nested case control study

International Journal of Preventive Medicine, 2013
Background: Respiratory tract infections are very common among the Hajj pilgrims. Some preventive measures including Influenza vaccination, using face mask and salt water gargling have been considered to control these infections and the reports show ...
Mohammad Hassan Emamian, Ali Mohammad Hassani, Mansooreh Fateh   +2 more
doaj  

Prevalence of respiratory pathogens in nasal swabs from horses with acute respiratory disease in Belgium [PDF]

, 2016
Contagious respiratory infections are an important cause of respiratory disease in horses, resulting in impaired pulmonary function, poor performance and sometimes severe illness.
Amory, H, Broux, Barbara, Deprez, Piet, Frippiat, T, Gasthuys, Frank, Gryspeerdt, Annick, Legrand, L, Pardon, Bart   +7 more
core  

Procalcitonin-guided antibiotic use versus a standard approach for acute respiratory tract infections in primary care: study protocol for a randomised controlled trial and baseline characteristics of participating general practitioners [ISRCTN73182671] [PDF]

, 2005
Matthias Briel, Mirjam Christ‐Crain, Jim Young, Philipp Schüetz, Peter Huber, Pierre Périat, Heiner C. Bucher, Beat P. Müller‐Stich   +7 more
openalex   +1 more source