Results 121 to 130 of about 423,863 (309)

Pharmacotherapy of acute respiratory viral infections

Терапевтический архив, 2013
The paper deals with the etiology, diagnosis, and treatment of acute respiratory viral infections (ARVI). It considers the currently available methods of etiotropic treatment and the tactics of antiviral therapy.
A A Zaĭtsev
doaj  

Enhancement of respiratory virus infection by air pollutants

Ecotoxicology and Environmental Safety
Viral respiratory infections are a leading cause of morbidity and mortality worldwide, posing significant economic and health burdens. This review examines how air pollutants promote viral respiratory infections and influence disease outcomes.
Ya-Fang Chiu, Chih-Chen Kao, Chi-Yuan Chen, Chia-Ping Su, Chia-Hao Ma, Yamin Kyaw, Jeng-How Yang   +6 more
doaj   +1 more source

SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening

Advanced Science, EarlyView.
Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen, Jiaqi Yu, Jing Xu, Lingqi Chen, Ninghao Zhang, Wenrui Li, Runmin Zeng, Xiaomin Luo, Yiqun Chang, Jiayin Lai, Wenshi Huang, Xiaochen Liang, Ting Zhao, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Xueqin Huang, Haibo Zhou, Junxia Zheng   +20 more
wiley   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

Efficacy of seasonal influenza vaccination in children in Hong Kong: a randomized controlled trial [PDF]

, 2012
BACKGROUND: Seasonal influenza vaccination is most effective in preventing influenza infection and disease in healthy school-age children when circulating strains are similar to those included in the vaccine.
So, T, Ip, DKM, Cheng, CKY, Wong, YT, Ma, ESK, Wai, W, Peiris, JSM, Cowling, BJ, Chiu, SSS, Leung, GM, Ng, S, Chan, KH, Fang, VJ   +12 more
core  

Lower respiratory tract infections in patients with comorbidities

, 2020
Comorbidities are an important factor of the various infectious respiratory diseases emergence, complications development and prognosis. The most frequent comorbidities affecting the course and outcome of respiratory infections are the following ...
Leonid I. Dvoretsky
core   +1 more source

Modeling respiratory viral infections actual in the first quarter of the XXI century: from primary epithelial cultures to organoids

Инфекция и иммунитет
Respiratory viral infections pose a serious public health issue resulting in high morbidity and mortality, as well as profound socioeconomic losses.
Tatyana A. Kuznetsova, A. A. Mikhalko, E. M. Shchelkanov, S. P. Kryzhanovsky, M. Yu. Shchelkanov   +4 more
doaj   +1 more source

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

Advanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang, Zenghui Cui, Yunkai Zhang, Zhiqing Li, Xuetao Cao   +4 more
wiley   +1 more source

Seasonal and pandemic influenza virus attack rates in a randomized placebo-controlled controlled trial of seasonal influenza vaccine

, 2010
The 12th International Symposium on Respiratory Viral Infections, Taipei, Taiwan, 11-14 March ...
Ng, S
core  

COVID-19 vaccination induces cross-reactive dengue virus antibodies with altered isotype profiles and in vitro antibody-dependent enhancement

Frontiers in Immunology
BackgroundSARS-CoV-2 infection and COVID-19 vaccination can induce antibodies that cross-react with dengue virus (DENV). Pre-existing IgG antibodies against DENV are known to enhance infection through antibody-dependent enhancement (ADE) via Fcγ ...
Sebastian Reinig, Chin Kuo, Sheng-Yu Huang, Kuei-Ching Hsiung, Kuei-Ching Hsiung, Po-Kai Chen, Etsuro Ito, Etsuro Ito, Etsuro Ito, Ing-Kit Lee, Ing-Kit Lee, Ching-Yen Tsai, Shu-Min Lin, Shu-Min Lin, Shin-Ru Shih, Shin-Ru Shih   +15 more
doaj   +1 more source