Results 241 to 250 of about 10,606,337 (342)

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Repeated application of bifocal transcranial alternating current stimulation improves network connectivity but not response inhibition: a double-blind sham control study. [PDF]

Cereb Cortex
Fujiyama H, Bowden VK, Tang AD, Tan J, Librizzi E, Loft S.   +5 more
europepmc   +1 more source

Growth inhibition of a B cell leukemia: evidence implicating an anti-idiotype immune response for protective tumor immunity. [PDF]

, 1986
Richard P. Ciavarra, E S Vitetta, J Forman   +2 more
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

The effects of isolated game elements on adherence rates in food response inhibition training. [PDF]

R Soc Open Sci
MacLellan A, Pennington CR, Lawrence N, Westwood SJ, Jones A, Slegrova A, Sung B, Parker L, Relph L, Miranda JO, Shakeel M, Mouka E, Lovejoy C, Chung C, Lash S, Suhail Y, Nag M, Button KS.   +17 more
europepmc   +1 more source

The balance equation: Part 1. Response-specific inhibition and the operant-contingency puzzles [PDF]

, 1987
Douglas Anger
openalex   +1 more source

Brain correlates of response inhibition in Internet gaming disorder

Psychiatry and Clinical Neurosciences, 2015
Chiao‐Yun Chen, Mei‐Feng Huang, J. Yen, Cheng-Sheng Chen, G. Liu, C. Yen, C. Ko   +6 more
semanticscholar   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

EMG-assessed paratonia: A novel approach to investigating motor response inhibition in healthy subjects. [PDF]

PLoS One
Puce L, Marinelli L, Currà A, Mori L, Schenone C, Cotellessa F, Tatarelli A, Pucci D, Bragazzi NL, Trompetto C.   +9 more
europepmc   +1 more source

Inhibition of human lymphoproliferative responses by mycobacterial phenolic glycolipids [PDF]

, 1989
Jean‐Jacques Fournié, Elizabeth M. Adams, Raymond J Mullins, Antony Basten   +3 more
openalex   +1 more source