Results 81 to 90 of about 7,596,663 (297)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Response inhibition, preattentive processing, and sex difference in young children: an event-related potential study

, 2013
Response inhibition and preattentive processing are two important cognitive abilities for child development, and the current study adopted both behavioral and electrophysiological protocols to examine whether young children's response inhibition ...
Shi, Jiannong, Xiao, Tong, Liu, Tongran, Shi, JN (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, 10A Datun Rd, Beijing 100101, Peoples R China.   +3 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The Impact of Dexamphetamine Treatment for Obesity on Executive Function: A Double-Blind Randomised Controlled Pilot Study

Brain Sciences
Background: Amphetamines increase dopamine levels in mid-brain regions which, in turn, impact top-down executive function. Repeated exposure is linked to substance use disorders.
Antoinette Poulton, Natalie Gauci, Hazer Khalifa, Emily J. Hibbert, Alison S. Poulton   +4 more
doaj   +1 more source

Fluctuating disinhibition: Implications for the understanding and treatment of alcohol and other substance use disorders

Frontiers in Psychiatry, 2013
Disinhibition is present in various maladaptive behaviours, including substance use disorders. Most previous research has assumed that disinhibition is a psychological construct that is relatively stable within individuals.
Andrew eJones, Paul eChristiansen, Chantal eNederkoorn, Katrijn eHouben, Matt eField   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Effect of drug-related cues on response inhibition through abstinence: A pilot study in male heroin abstainers

, 2017
Background: Chronic heroin use can cause a deficit of inhibitory function, leading to a loss of control over drug use. Exposure to drug-related cues is considered as one of the contributing factors.
Ling Yang, Su, Bobo, Li, Shaomei, Hua Cao, Sha Wang, Shaomei Li, Bobo Su, Wang, Sha, Yan Zhang, Wang, Grace Y., Zhang, Yan, Grace Y. Wang, Yang, Ling, Cao, Hua   +13 more
core   +1 more source

The practice of going helps children to stop:The importance of context monitoring in inhibitory control [PDF]

, 2014
How do we stop ourselves during ongoing action? Recent work implies that stopping per se is easy given sufficient monitoring of contextual cues signaling the need to change action.
Chevalier, Nicolas, Munakata, Yuko, Chatham, Christopher H   +2 more
core   +1 more source

Effect of foreknowledge on neural activity of primary go responses relates to response stopping and switching

Frontiers in Human Neuroscience, 2015
Being able to stop (or inhibit) an action rapidly as in a stop-signal task is an essential human ability. Previous studies showed that when a pre-stimulus cue warned of the possible need to stop a response in an upcoming trial, participants’ response ...
Benjamin eXu, Sarah eLevy, John eButman, Dzung ePham, Dzung ePham, Leonardo G Cohen, Marco eSandrini, Marco eSandrini   +7 more
doaj   +1 more source

Comparison of executive functions in addicted young people who referred to addiction treatment camps with students

Cogent Psychology, 2020
Background and aim: Cerebral areas related to executive functions, during adolescence and early youth encounter with structural and functional changes and fluctuations that expose adolescents to many problems including drug abuse.
Abdollah Salmani, Mghsoud Nader pilehroud, Maryam jammali   +2 more
doaj   +1 more source