Results 91 to 100 of about 13,505,920 (341)

Fronto-striatal circuits in response-inhibition: Relevance to addiction

Brain Research, 2015
Disruptions to inhibitory control are believed to contribute to multiple aspects of drug abuse, from preexisting vulnerability in at-risk individuals, through escalation to dependence, to promotion of relapse in chronic users. Paradigms investigating the
S. Morein-Zamir, T. Robbins
semanticscholar   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

The impact of emotional stimuli on response inhibition in an inpatient and day-hospital patient psychosomatic cohort

Frontiers in Psychiatry, 2023
ObjectivesTo correctly recognize and respond to your counterpart's emotion is essential for a successful get-together. To ensure this, emotional processes and inhibitory control are linked and interact with each other.
Sina Westbomke, Kathrin Schag, Birgit Derntl, Stephan Zipfel, Andreas Stengel, Andreas Stengel   +5 more
doaj   +1 more source

Alcohol affects neuronal substrates of response inhibition but not of perceptual processing of stimuli signalling a stop response [PDF]

, 2013
Alcohol impairs inhibitory control, including the ability to terminate an initiated action. While there is increasing knowledge about neural mechanisms involved in response inhibition, the level at which alcohol impairs such mechanisms remains poorly ...
A Green, A Hampshire, A Mehrabian, A Nambu, A Rey, AD Chevrier, AJ Caswell, AL Norman, AR Aron, AR Aron, AR Aron, AR Aron, AR Aron, BM Anderson, C Easdon, CA Marczinski, CA Marczinski, CA Marczinski, CD Chambers, CM Dodds, CM Steele, CN Boehler, CN Boehler, CN White, CR Guillot, CS Li, DJ Sharp, DM Dougherty, DM McCarthy, DM Torta, F Esposito, F Verbruggen, F Verbruggen, GD Logan, GE Alexander, GE Alexander, H de Wit, HM Duvernoy, Hugo Critchley, J Ashburner, J Chikazoe, J Weafer, JH Patton, JL Kenemans, JM Townshend, K Fromme, K Katanoda, K Marinkovic, K Nikolaou, K Rubia, KJ Friston, Kyriaki Nikolaou, L Boucher, LE Mulvihill, M Field, M Sano, MA Schuckit, Marcus Gray, MC Stevens, MT Fillmore, MT Fillmore, N Weiskopf, ND Volkow, NH Naqvi, R Deichmann, R Weissenborn, RB Buxton, RN Henson, RS Ross, RZ Goldstein, S Loeber, S Loeber, S Loeber, SC Matthews, SD Slotnick, T Duka, T Nichols, T Singer, Theodora Duka   +78 more
core   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Primary cilia elongation in response to interleukin-1 mediates the inflammatory response [PDF]

, 2012
Primary cilia are singular, cytoskeletal organelles present in the majority of mammalian cell types where they function as coordinating centres for mechanotransduction, Wnt and hedgehog signalling. The length of the primary cilium is proposed to modulate
A. K. T. Wann, AC Lin, AJ Espanol, AM Malone, BD Engel, BK Yoder, CA Dinarello, CG Jensen, CM Asleson, D Qian, DA Lee, E Verghese, E Verghese, EJ Michaud, EM Mokrzan, GJ Pazour, H Tukachinsky, I Memon, J Kim, JA Deane, JL Rosenbaum, JM Neugebauer, K Gardner, KJ Palmer, L Schneider, M Barzi, M Cao, M. M. Knight, MA Lancaster, MB Hovater, N Sharma, P Tummala, PA Lefebvre, PV Tran, RY Kwon, S Abdul-Majeed, S Agarwal, S Kim, S Massinen, S Mukhopadhyay, S Pritchard, S Toffoli, SC Goetz, SM Nauli, SR McGlashan, SR McGlashan, SR McGlashan, TT Chowdhury, TY Besschetnova, Y Chen, Y Ou, YH Choi   +51 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Tonic inhibition of accumbal spiny neurons by extrasynaptic 4 GABAA receptors modulates the actions of psychostimulants [PDF]

, 2014
Within the nucleus accumbens (NAc), synaptic GABAA receptors (GABAARs) mediate phasic inhibition of medium spiny neurons (MSNs) and influence behavioral responses to cocaine.
Belelli, D, Dixon, C I, Herd, M B, King, S L, Lambert, J J, MacPherson, T, Maguire, E P, Stephens, D N, Swinny, J D   +8 more
core   +1 more source

Response Inhibition in Smokers

Advances in Psychological Science, 2015
近期研究发现，吸烟会使个体的反应抑制能力受到一定程度的影响。与不吸烟的健康人群相比，吸烟者在测量反应抑制能力的Go/NoGo任务和Stop-Signal任务上的虚报率较高，反应时间较长；吸烟者的反应抑制能力在反应抑制加工阶段受到影响，而在冲突监控阶段并未与正常被试表现出差异；另外，研究还发现，与不吸烟者相比，吸烟者左侧丘脑、左侧额中回和左侧前扣带回灰质体积较小。尼古丁的摄入对前额叶和中脑边缘多巴胺系统的影响可能是导致吸烟者反应抑制能力受到影响的原因。但是，一些研究并未发现吸烟对反应抑制能力存在影响，这可能与实验任务以及研究对象的选取有关。比较不同香烟剥夺状态下个体的反应抑制能力、比较吸烟者与其他药物成瘾者（酒精、毒品）反应抑制能力的差异并且比较使用双选择oddball范式与 Go/NoGo 任务和 ...
Xin ZHAO, Xiaoting LIU, Xiangyi ZAN, Aibao ZHOU   +3 more
openaire   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source