Results 101 to 110 of about 5,779,443 (305)
Evaluation of treatment response in adults with relapsing MOG-Ab-associated disease
Journal of Neuroinflammation, 2019 Background Myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) are related to several acquired demyelinating syndromes in adults, but the therapeutic approach is currently unclear. We aimed to describe the response to different therapeutic strategies
Alvaro Cobo-Calvo +26 more
doaj +1 more source
Estimating the Effects of Lenght of Exposure to Traning Program: The Case of Job Corps [PDF]
Length of exposure to a training program is important in determining the labor market outcomes of participants. Employing methods to estimate the causal effects from continuous treatments, we provide insights regarding the effects of different lengths of
Arturo Gonzalez +3 more
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Propensity Score Matching with Limited Overlap [PDF]
In this article, we have demostrated the application of two newly proposed estimators which accounts for lack of overlap under propensity score matching on a case study involing the analysis of health expenditure data for the United States.
Onur Baser
core
Propensity score adjusted method for missing data [PDF]
, 2015 Propensity score adjustment is a popular technique for handling unit nonresponse in sample surveys. When the response probability does not depend on the study variable that is subject to missingness, conditional on the auxiliary variables that are ...
Riddles, Minsun
core +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Maternal smoking during pregnancy and birthweight - A propensity score matching approach [PDF]
There is accumulated evidence of the existence of a deleterious effect of smoking on birth outcomes. Understanding the effect of smoking on pregnancy is a critical issue because of the public policy implications for dissuading maternal smoking.
Ronald P. Wilder, Paula Veiga
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Adaptive Experimental Design Using the Propensity Score [PDF]
Many social experiments are run in multiple waves, or are replications of earlier social experiments. In principle, the sampling design can be modified in later stages or replications to allow for more efficient estimation of causal effects.
Keisuke Hirano +2 more
core +2 more sources
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source