Results 71 to 80 of about 1,717,018 (297)

Joint factor of basalt and its relationship with strength and deformation characteristics

Yantu gongcheng xuebao
The joint density, joint inclination angle and joint roughness are the three key factors that control the mechanical response of basalts. Based on the 3D printing technology, the uniaxial compression and interfacial shear tests are carried out to deeply ...
KONG Yang 1, RUAN Huaining 2, ZHANG Guirong 1, HE Ning 1, WANG Zhangchun 1
doaj   +1 more source

Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression

Neurobiology of Disease, 2005
Although macrophages are mediators of CNS demyelination, they are also implicated in remyelination. To examine the role of macrophages in CNS remyelination, adult rats were depleted of monocytes using clodronate liposomes and demyelination induced in the
Mark R. Kotter, Chao Zhao, Nico van Rooijen, Robin J.M. Franklin   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Derivation of Vertical Damping Reduction Factors for the Design and Analysis of Structures Using Acceleration, Velocity, and Displacement Spectra

Applied Sciences
Damping reduction factors (DRFs) play a vital role in the seismic design of structures. DRFs have been widely studied due to their primary importance to the lateral resistance of structures subjected to earthquakes.
Aicha Rouabeh, Baizid Benahmed, Mehmet Palanci, Issam Aouari   +3 more
doaj   +1 more source

The positive mental health instrument: development and validation of a culturally relevant scale in a multi-ethnic asian population

Health and Quality of Life Outcomes, 2011
Background Instruments to measure mental health and well-being are largely developed and often used within Western populations and this compromises their validity in other cultures.
Vaingankar Janhavi, Subramaniam Mythily, Chong Siow Ann, Abdin Edimansyah, Orlando Edelen Maria, Picco Louisa, Lim Yee Wei, Phua Mei Yen, Chua Boon Yiang, Tee Joseph YS, Sherbourne Cathy   +10 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A Displacement-based Strength Reduction Factor for High-rise Steel Moment-Resisting Frames

, 2012
[[abstract]]A preliminary study of the ‘displacement-based strength reduction factor’ for high-rise steel momentresisting frames is presented in this paper.
童士恒, Lee, Wen-Hae, Yu, Chau-Cho
core  

Pre-reduction of Titanium Concentrate with Pulverized Coal and Iron Power Based on Response Surface Methodology Method

Kuangchan zonghe liyong
This is an article in the field of metallurgical engineering. The single factor and response surface experiments of heating reduction of titanium concentrate powder adding pulverized coal and iron powder were carried out, respectively so as to study the ...
Fuhong ZENG, Lanhua ZHOU
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source