Results 51 to 60 of about 7,311,002 (240)
Volume 4, Number 1 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1006/thumbnail ...
Spectrum Contributors,
core +1 more source
Development of Seismic Demand for Chang-Bin Offshore Wind Farm in Taiwan Strait
Taiwan is located on the Pacific seismic belt, and the soil conditions of Taiwan’s offshore wind farms are softer than those in Europe. To ensure safety and stability of the offshore wind turbine supporting structures, it is important to assess the ...
Yu-Kai Wang +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Volume 2, Number 1 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1002/thumbnail ...
Spectrum Contributors,
core +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
In the earthquakes that occurred in the Pazarcık (Mw = 7.7) and Elbistan (Mw = 7.6) districts of Kahramanmaraş Province on 6 February 2023, many buildings collapsed in the Hayrullah neighborhood of the Onikişubat district.
Eyübhan Avcı +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Volume 6, Number 1 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1010/thumbnail ...
Spectrum Contributors,
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

