Results 61 to 70 of about 7,311,002 (240)
Seismic safety analysis of the Guazhou pump station
Nantong Daxue xuebao. Ziran kexue banThe Guazhou pump station, a representative project awarded the Luban Prize, plays a crucial role in flood control and drainage in the urban area of Yangzhou.
WU Hao; LI Baochun; YUAN Cong; XIA Guochun; WU Yongjun; HUANG Kai; ZHANG Wei; QIU Jianchun
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
, 1992 Literary journalhttps://nwcommons.nwciowa.edu/spectrum/1018/thumbnail ...
Spectrum Contributors,
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Dizhen xuebao为探究不同场地类别对反应谱特征周期的影响，建立了包含四种场地类别的180个计算剖面，在现行 《建筑抗震设计规范》 GB 50011—2010中场地分类的基础上按照土的软硬程度进一步细分，以不同幅值的El Centro地震动作为输入地震动，采用一维等效线性化方法进行土层反应分析，计算得到场地地震动反应谱，规准化得到反应谱特征周期。结果表明：① 在同一类别场地中，随着等效剪切波速的增大，特征周期呈减小的趋势；② 在同一类别场地中，随着输入地震动强度的增大，特征周期也相应增大；③ 在不同类别场地中 ...
Ping Li +5 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
, 1981 Volume 3, Number 2 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1004/thumbnail ...
Spectrum Contributors,
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
, 1988 Literary journalhttps://nwcommons.nwciowa.edu/spectrum/1012/thumbnail ...
Spectrum Contributors,
core +1 more source