Results 61 to 70 of about 2,820,746 (300)

A Comparison Analysis of Buildings as per Norwegian and Ethiopia ES-EN1998-1 Seismic Code

open access: yesBuildings
An earthquake is one of the most significant and shocking natural disasters ever documented anywhere on the planet. Throughout history, it has claimed millions of lives and wreaked devastation on infrastructure.
Mistreselasie Abate   +2 more
doaj   +1 more source

Chaotic response of global climate to long-term solar forcing variability

open access: yes, 2009
It is shown that global climate exhibits chaotic response to solar forcing variability in a vast range of timescales: from annual to multi-millennium. Unlike linear systems, where periodic forcing leads to periodic response, nonlinear chaotic response to
Bershadskii, A.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Retrofitting of a Multi-Span Simply Supported Bridge into a Semi-Integral Bridge

open access: yesApplied Sciences
Thousands of multi-span, simply supported beam bridges with short or medium spans have been built in China. They often suffer from problems of cracks in the link slabs over piers, and the deterioration and damage of deck expansion joints at abutments. To
Zhen Xu   +4 more
doaj   +1 more source

Derivation of equivalent linear properties of Bouc-Wen hysteretic systems for seismic response spectrum analysis via statistical linearization [PDF]

open access: yes, 2013
A newly proposed statistical linearization based formulation is used to derive effective linear properties (ELPs), namely damping ratio and natural frequency, for stochastically excited hysteretic oscillatorsinvolving the Bouc-Wen force-deformation ...
Giaralis, A., Spanos, P. D.
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Development of Geotechnical Seismic Isolation System in the Form of Vertical Barriers: Effectiveness and Perspective

open access: yesBuildings
This paper discusses the concept of geotechnical seismic isolation (GSI) systems, characterized by new principles of action, to reduce seismic loads on buildings.
Yerik T. Bessimbayev   +7 more
doaj   +1 more source

The INTEGRAL/SPI response and the Crab observations [PDF]

open access: yes, 2004
The Crab region was observed several times by INTEGRAL for calibration purposes. This paper aims at underlining the systematic interactions between (i) observations of this reference source, (ii) in-flight calibration of the instrumental response and ...
Attie, D.   +10 more
core   +3 more sources

Inter-rater reliability of treatment fidelity and therapeutic alliance measures for psychological therapies for anxiety in young people with autism spectrum disorders [PDF]

open access: yes, 2014
Objectives: This article presents work undertaken to establish inter-rater reliability for a measure of treatment fidelity and a measure of therapeutic alliance for therapies for anxiety for young people with autism spectrum disorders. The discussion and
Brown, Rachel   +7 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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