Results 51 to 60 of about 2,257,568 (316)

Optimize the Ultrasonic-assisted Extraction Process for Total Triterpenoids from Lavandula angustifolia and Its Antioxidant Activity in Vitro

open access: yesShipin gongye ke-ji, 2022
In order to increase the utilization value of Lavandula angustifolia (LA) residue and provide a theoretical basis for the development and utilization of LA waste, the extraction process of total triterpenoids from LA was optimized and its antioxidant ...
Yadikar NIGARY   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Application of response surface methodology to stiffened panel optimization [PDF]

open access: yes, 2006
In a multilevel optimization frame, the use of surrogate models to approximate optimization constraints allows great time saving. Among available metamodelling techniques we chose to use Neural Networks to perform regression of static mechanical criteria,
Samuelides, Manuel   +5 more
core   +1 more source

Fe-mediated DOM components drive effective arsenic immobilization in tea plantation soils: Mechanisms and quantitative insights

open access: yesEcotoxicology and Environmental Safety
In iron (Fe)-rich tea plantation environments, the composition and behaviour of dissolved organic matter (DOM) differ markedly from those observed in other land use systems. Despite its importance, research on DOM in tea plantation soils remains limited,
Jingyi Zhang   +7 more
doaj   +1 more source

Extraction Process Optimization, Active Ingredient Screening and Structure Study of Dendrobium officinale Protein

open access: yesShipin gongye ke-ji, 2022
To explore the repairing effect of Dendrobium officinale protein on the injured rat gastric mucosa epithelial cells after the extraction process was optimized.
Jing ZENG   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Optimization of Streptomyces sp.A11 Medium Cultivation on Cyclo(Tyrosyl-Prolyl) Production Using the Response Surface Methodology [PDF]

open access: yes, 2012
The Response Surface Methodology is a three factorial design which provides the relationship between one or more measured dependent response and a number of input (independent) factors.
Rofiq , Sunaryanto
core  

Optimization of xylanase production by Sporotrichum thermophile using corn cobs and response surface methodology

open access: yes, 2006
A 32 central composite experimental design was performed with the aim of optimizing the production of xylanase by Sporotrichum thermophile grown on corn cobs in submerged cultures.
Katapodis, P   +5 more
core   +1 more source

Mapping field-scale daily evapotranspiration using unbiased spatio-temporal fusion approach over heterogeneous surface

open access: yesGIScience & Remote Sensing
Accurate estimation of daily evapotranspiration (ET) at the field scale is essential for agricultural water management, particularly in arid and semi-arid regions, yet existing satellite products often suffer from spatiotemporal trade-offs.
Aoxiang Guo   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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