Results 61 to 70 of about 2,257,568 (316)

Impacts of climate change on surface ozone and intercontinental ozone pollution : a multi-model study [PDF]

, 2013
The impact of climate change between 2000 and 2095 SRES A2 climates on surface ozone (O)3 and on O3 source-receptor (S-R) relationships is quantified using three coupled climate-chemistry models (CCMs).
Stevenson, D. S., Stevenson, D. S.; id_orcid, Derwent, R. G., Doherty, R. M., Wild, O., Zeng, G., Dentener, F. J., Schultz, M. G., Collins, W. J., MacKenzie, I. A., Fiore, Arlene M., Schultz, Martin, Fiore, A. M., Shindell, D. T., Hess, P., Keating, T. J.   +15 more
core   +1 more source

Combination Mechanism of Soil Dissolved Organic Matter and Cu²⁺ in Vegetable Fields, Forests and Dry Farmland in Lujiang County

Agriculture
Dissolved organic matter (DOM) serves as a critical link in the migration and transformation of heavy metals at the soil–solid interface, influencing the migration behaviour and transformation processes of Cu2+ in soil.
Youru Yao, Jingyi Zhang, Kang Ma, Jing Li, Xin Hu, Yusi Wang, Yuesheng Lin, Fengman Fang, Shiyin Li   +8 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Using response-surface methodology to detect chaos in ecological time series

, 1993
The performance of Turchin and Taylor's response-surface methodology in characterizing the endogenous dynamics underlying ecological time series is studied for the aphid Phyllaphis fagi. The results are shown to be sensitive to further data from the same
Hanski, I., Perry, J. N., Woiwod, I. P.
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Hillside urban expansion exacerbates nature and semi-nature habitat landscape fragmentation in China

International Journal of Digital Earth
Hillside urban expansion (HUE) force nature and semi-nature habitats (referred as nature habitats) to migrate to higher slope areas, potentially resulting in modifications to the landscapes of these habitats, and affect biodiversity and human well-being.
Zhijian Chang, Lili Liu, Jinji Ma, Weidong Cao, Yuanzheng Cui, Kaifang Shi   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Reference evapotranspiration prediction using high-order response surface method

, 2022
The precision of reference evapotranspiration (ETo) predictions would vary, depending on the adopted empirical method and the availability of meteorological data.
Saggi, Mandeep Kaur, Yaseen, Zaher Mundher, Huang, Yuk Feng, Khedher, Khaled Mohamed, Abdullah, Shafika Sultan, Keshtegar, Behrooz   +5 more
core   +1 more source

Reservoir impoundment alters surrounding plant physiological activities revealed by stable isotopes in tree rings

Ecological Indicators
Reservoir impoundment influences the growth of surrounding plants by altering the microclimate. However, the physiological mechanism of responses remains unclear.
Lian Sun, Yanpeng Cai, Yesi Zhao, Zixun Qi, Xinsheng Liu, Hongkai Gao, Lu Wang, Suyan Dai, Siyuan Lu, Jiejun Wang, Xijie Yin   +10 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source