Results 71 to 80 of about 4,922,205 (297)

Aging and reduced bulk conductance in thin films of the topological insulator Bi$_2$Se$_3$

, 2012
We report on the effect of exposure to atmospheric conditions on the THz conductivity of thin films of the topological insulator Bi$_2$Se$_3$. We find: 1) two contributions of mobile charge carriers to the THz conductivity immediately after growth, and 2)
Aguilar, R. Valdés, Armitage, N. P., Bansal, N., Bilbro, L. S., Brahlek, M., Oh, S., Stier, A. V., Wu, L.   +7 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Reservoir impoundment alters surrounding plant physiological activities revealed by stable isotopes in tree rings

Ecological Indicators
Reservoir impoundment influences the growth of surrounding plants by altering the microclimate. However, the physiological mechanism of responses remains unclear.
Lian Sun, Yanpeng Cai, Yesi Zhao, Zixun Qi, Xinsheng Liu, Hongkai Gao, Lu Wang, Suyan Dai, Siyuan Lu, Jiejun Wang, Xijie Yin   +10 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Estimation of agricultural flood irrigation water consumption in the Heihe River Basin, China, using satellite based daily land surface evapotranspiration and soil moisture

Journal of Hydrology: Regional Studies
Study region: The Heihe River Basin, China. Study focus: Irrigation data are often from census surveys at coarse administrative or river basin scale, and as such, the amount of water used for agricultural irrigation difficult to quantify.
Lirong Huo, Qiaoyun Xie, Liang Sun, Lisheng Song, Sinuo Tao, Shaomin Liu, Zuo Wang, Yan Li   +7 more
doaj   +1 more source

Anisotropic optical response of the diamond (111)-2x1 surface

, 1995
The optical properties of the 2$\times$1 reconstruction of the diamond (111) surface are investigated. The electronic structure and optical properties of the surface are studied using a microscopic tight-binding approach.
A. I. Shkrebtii, A. Selloni, A. Selloni, A.G. Bagchi, A.R. Turner, B.B. Pate, B.B. Pate, B.N. Davidson, C. Kress, C. Noguez, C. Noguez, Cecilia Noguez, D. Vanderbilt, D.A. Drabold, D.A. Drabold, D.E. Aspnes, D.R. Alfonso, F. Ancilotto, F. Bassani, F. Manghi, F.G. Celii, F.J. Himpsel, G.B. Adams, G.D. Kubiak, H. Ibach, J.D. Jackson, J.D.E. McIntyre, J.E. Northrup, J.E. Northrup, J.F. Morar, J.M. Nicholls, K.C. Pandey, M. Roy, N. Takeuchi, O.F. Sankey, P. Chiaradia, P. Vogl, P.G. Lurie, Ph. Hofmann, R. Del Sole, R. Del Sole, R. Del Sole, R. Stumpf, R.I. Uhrberg, S. Iarlori, S.V. Pepper, S.V. Pepper, Sergio E. Ulloa, T. Yasuda, V.I. Gavrilenko, W.L. Mochán, W.L. Mochán, W.L. Mochán, W.L. Schaich, Y. Borensztein   +54 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A Spatial-Temporal Seamless Evapotranspiration Product Based on TSEB-SM Model and DNN-ETo Method Across China

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Accurate, seamless products of evapotranspiration (ET) are crucial for understanding the hydrological and energy cycles. Currently, there is no routinely available daily ET product based on the thermal infrared satellite data and two-source energy ...
Gengle Zhao, Lisheng Song, William P. Kustas, Long Zhao, Shaomin Liu, Gaofei Yin, Rongqi Tang   +6 more
doaj   +1 more source