Results 101 to 110 of about 657,782 (299)

Sliced rotated sphere packing designs

, 2017
Space-filling designs are popular choices for computer experiments. A sliced design is a design that can be partitioned into several subdesigns. We propose a new type of sliced space-filling design called sliced rotated sphere packing designs. Their full
He, Xu
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Use of Chitosan and Chitosan–Magnetite Spheres for Arsenic Groundwater Removal: Factorial Designs as Tools to Optimize the Efficiency of Removal

Inorganics
The lack of access to drinking water is a problem affecting many regions worldwide. In Santa Fe, Argentina, the population uses groundwater as a source of drinking water.
Mayra Hernández Trespalacios, María Florencia Mangiameli, Lina Gribaudo, María Inés Frascaroli, Juan Carlos González   +4 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Evaluating the prediction power and accuracy of two smart response surface experimental designs after revisiting repaglinide floating tablets

Future Journal of Pharmaceutical Sciences
Background There is a soar in the figure of companies aiming to achieve efficiency in undergoing experimental processes. Therefore, instead of deploying one-factor-at-a-time, design of experiments is becoming rampantly utilized in order to reduce the ...
Tarek Elsayed, Rania M. Hathout
doaj   +1 more source

Ultrasound-assisted extraction of polyphenols from Phyllanthi Fructus: Comprehensive insights from extraction optimization and antioxidant activity

Ultrasonics Sonochemistry
Phyllanthi Fructus (PF) is a valuable botanical resource with a long history of traditional use, known for potent antioxidant and anti-inflammatory effects attributed to its rich contents of bioactive compounds, particularly polyphenols. However, current
Haixia Che, Rui Zhang, Xianyao Wang, Hong Yu, Xuepeng Shi, Jie Yi, Jiawen Li, Qi Qi, Ruizhi Dong, Qian Li   +9 more
doaj   +1 more source

Lab-Scale Fiber Spinning Experimental Design Cost Comparison [PDF]

Journal of Engineered Fibers and Fabrics, 2010
Many statistical experimental designs are too costlyor require too much raw material to be feasible forlab-scale fiber spinning experiments. In this study afour-factor response surface design is presented tostudy the fiber spinning process in detail at ...
Jeffrey C. Moreland, Julia L. Sharp, Ph.D., Philip J. Brown, Ph.D.   +2 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Tuning structural dynamics through architected inner material designs: Numerical, experimental, and machine learning analysis

Materials & Design
Architected materials and structures have garnered significant interest due to their potential to furnish mechanical performances beyond the bounds of customary designs.
Irfan Ul Hassan, Agyapal Singh, Dimitrios C. Rodopoulos, Alexander Morawietz, Andrea Bergamini, Nikolaos Karathanasopoulos   +5 more
doaj   +1 more source

Exploiting correlation in the construction of D-optimal response surface designs. [PDF]

Cost considerations and difficulties in performing completely randomized experiments often dictate the necessity to run response surface experiments in a bi-randomization format.
Goos, Peter, Vandebroek, Martina
core