Results 91 to 100 of about 657,782 (299)
Optimized multi-objective design of herringbone micromixers [PDF]
, 2009 This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009) +2 more
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RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Modeling and synthesis of multicomputer interconnection networks [PDF]
The type of interconnection network employed has a profound effect on the performance of a multicomputer and multiprocessor design. Adequate models are needed to aid in the design and development of interconnection networks.
Auxter, D. Steve, Standley, Hilda M.
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Multi-objective robust concept exploration within the made-to-order sector [PDF]
, 1999 Concept exploration is an activity of fundamental importance when designing large, complex made-to-order engineering products. At the concept design stage of the design process, it is essential that many design alternatives are evaluated.
Coates, Graham +2 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Numbers of center points appropriate to blocked response surface experiments [PDF]
Tables are given for the numbers of center points to be used with blocked sequential designs of composite response surface experiments as used in empirical optimum seeking. The star point radii for exact orthogonal blocking is presented. The center point
Holms, A. G.
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The application of multi-objective robust design methods in ship design [PDF]
, 1999 When designing large complex vessels, the evaluation of a particular design can be both complicated and time consuming. Designers often resort to the use of concept design models enabling both a reduction in complexity and time for evaluation.
Coates, Graham +2 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Predicting the Onset of Cavitation in Automotive Torque Converters—Part II: A Generalized Model
International Journal of Rotating Machinery, 2008 The objective of this investigation was to develop a dimensionless model for predicting the onset of cavitation in torque converters applicable to general converter designs.
D. L. Robinette +5 more
doaj +1 more source
Kriging Metamodeling in Simulation: A Review [PDF]
This article reviews Kriging (also called spatial correlation modeling). It presents the basic Kriging assumptions and formulas contrasting Kriging and classic linear regression metamodels.
Kleijnen, J.P.C.
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