Results 71 to 80 of about 657,782 (299)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Gendex: FFD Module for Constructing Orthogonal or Near-Orthogonal Fractional Replicate and Response Surface Treatment Designs [PDF]
, 2001 14 pages, 1 article*Gendex: FFD Module for Constructing Orthogonal or Near-Orthogonal Fractional Replicate and Response Surface Treatment Designs* (Federer, Walter T.; Nguyen, Nam-Ky; Nshinyakabeje, Sophonie) 14 ...
Cornell University. Biometrics Unit. +5 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
APPLICATION OF EXPERIMENTS PLANNING IN THE MINERAL PROCESSING
Rudarsko-geološko-naftni Zbornik, 2004 Statistical design of experiments deals with methods of planning the experiment so that appropriate data are collected, which may be analyzed by statistical methods resulting in objective and valid conclusions.
Slavka Pfaff, Branko Salopek
doaj
Robust Speed Control of PMSM Using Sliding Mode Control (SMC)—A Review
Energies, 2019 Permanent magnet synchronous motors (PMSMs) are known as highly efficient motors and are slowly replacing induction motors in diverse industries. PMSM systems are nonlinear and consist of time-varying parameters with high-order complex dynamics.
Fardila Mohd Zaihidee +2 more
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Optimum Simplex Lattice Designs of Low Order Multiresponse Surface Model by D-Optimum Criterion
Jurnal Ilmu Dasar, 2010 Simplex lattice design is a part of mixture designs has patterns simplex {q, m} where q is number of factors andm is degree of polynomial. If entangling a number of the response variables which measured from a number offactors called the multiresponse ...
Ruslan Ruslan +3 more
doaj
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Advanced Electrical and Optical Microsystems for Biointerfacing
Advanced Intelligent Systems, 2020 Electrical and optical biointerfaces have contributed considerably to understanding biological systems. Recent advances in biocompatible materials, structure designs, and fabrication techniques have established flexible and minimally invasive electronic ...
Sofian N. Obaid, Zhiyuan Chen, Luyao Lu
doaj +1 more source