Results 51 to 60 of about 657,782 (299)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Glutamic acid assisted hydrolysis strategy for preparing prebiotic xylooligosaccharides

Frontiers in Nutrition, 2022
Since the immune-boosting properties as well as the benefit of promoting the growth of gut bacteria, xylooligosaccharides as prebiotics have attracted considerable interest as functional feed additives around the world.
Rong Huang, Rui Zhang, Rui Zhang, Shuangquan Yao, Mengyuan Si, Ruowen Xia, Xin Zhou, Xingli Fan, Kankan Jiang   +8 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Interface Design of SnO2@PANI Nanotube With Enhanced Sensing Performance for Ammonia Detection at Room Temperature

Frontiers in Chemistry, 2020
Gas sensors with excellent stability and a high response at room temperature has drawn a great deal of attention and demand for them is huge. Surface designs provide inspiration toward making more useful sensor devices. The facile electrospinning process
Anqiang Jia, Anqiang Jia, Anqiang Jia, Bitao Liu, Haiyan Liu, Qiufeng Li, Yingxia Yun   +6 more
doaj   +1 more source

Medium Optimization for GA4 Production by Gibberella fujikuroi Using Response Surface Methodology

Fermentation, 2022
Gibberellin is an important plant growth regulator that has been widely used in agricultural production with great market prospects. However, the low yield from Gibberella fujikuroi restricts its application.
Bingxuan Wang, Kainan Yin, Choufei Wu, Liang Wang, Lianghong Yin, Haiping Lin   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Variance exchange process: overcoming the problem of singular information matrices in quadratic three−variable response designs

Journal of Innovative Applied Mathematics and Computational Sciences
Many a time, in a variance exchange process looking for D-optimal designs, the initial designs of all quadratic components of three-variable response polynomials produce non-invertible information matrices.
Okim Ikpan, Felix Nwobi
doaj   +1 more source

Non-linear autopilot design using the philosophy of variable transient response [PDF]

, 2009
The novel non-linear controller design methodology of Variable Transient Response (VTR) is presented in this research. The performance of VTR is compared to that of successful non-linear controller designs (such as Robust Inverse Dynamics Estimation and ...
Brindley, Joseph, Counsell, John M., Macdonald, Malcolm   +2 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Re-Modeling of a Polymeric Drug Delivery System Using Smart Response Surface Designs: A Sustainable Approach for the Consumption of Fewer Resources

ChemEngineering
Introduction: The use of response surface designs for drug formulation is highly warranted nowadays. Such smart designs reduce the number of required experiments compared to full-factorial designs, while providing highly accurate and reliable results ...
Magdy M. Aly, Shaimaa S. Ibrahim, Rania M. Hathout   +2 more
doaj   +1 more source