Results 41 to 50 of about 657,782 (299)

Effects of missing observations on predictive capability of central composite designs

, 2014
Quite often in experimental work, many situations arise where some observations are lost or become unavailable due to some accidents or cost constraints.
Adebayo, Bamiduro Timothy, Chukwu, Angela Unna, Nwanzo, Amahia Godwin, Yakubu, Yisa   +3 more
core   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

The CARSO (Computer Aided Response Surface Optimization) Procedure in Optimization Studies [PDF]

, 2015
The paper illustrates innovative ways of using the CARSO (Computer Aided Response Surface Optimization) procedure for response surfaces analyses derived by DCM4 experimental designs in multivariate spaces.
Baroni, Massimo, Bazzurri, Matteo, Benedetti, Paolo, Chiocchini, Danilo, Clementi, Sergio ., Decastri, Diego, Ebert, Cynthia, Fernandi, Mauro, Gardossi, Lucia, Randazzo, Giuseppe Marco   +9 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Preliminary Investigation of the Frictional Response of Reptilian Shed Skin

, 2012
Developing deterministic surfaces relies on controlling the structure of the rubbing interface so that not only the surface is of optimized topography, but also is able to self-adjust its tribological behaviour according to the evolution of sliding ...
Abdel-Aal, Abdel-Aal, Abdel-Aal, Adams, Akay, Aubert, Berthé, Bhushan, Gorb, H. Zahouani, H.A. Abdel-Aal, Harkewicz, Hazel, Irish, Jiang, Jiang, Kumazawa, Le Bot, M. El Mansori, R. Vargiolu, Vidal, Vitt, Wu, Yokoi, Zahouani, Zhang   +25 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Statistical modeling and optimization of ultrasound-assisted biodiesel production using various experimental designs

Zaštita Materijala, 2019
The present study compares the performances of the regression models developed by the response surface methodology combined with the full factorial, Box-Behnken or face central composite designs applied for the ultrasound-assisted KOH-catalyzed ...
Vlada B. Veljković, Dragana B. Radosavljević, Ivan J. Stojković   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Reclaiming Wetlands after Oil Sands Mining in Alberta, Canada: The Changing Vegetation Regime at an Experimental Wetland

Land, 2022
Surface mining for oil sand results in the formation of large pits that must be reclaimed. Some of these pits are backfilled with a myriad of substrates, including tailings rich in cations and anions, to form a solid surface.
Melissa House, Dale H. Vitt, Lilyan C. Glaeser, Jeremy A. Hartsock   +3 more
doaj   +1 more source