Results 31 to 40 of about 1,694 (248)
Monte Carlo Comparison of Rival Experimental Designs For Two-Agent Combined Action Studies
Canadian Journal of Infectious Diseases, 1994 OBJECTIVE: The combined action of two or more chemotherapeutic agents and/or biological agents can be quantitatively described wilh empirical multidimensional concenlration-effect response surface models.
William R Greco +8 more
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Materials & Design, 2019 Triply Periodic Minimal Surface (TPMS) structures fabricated via Additive Manufacturing (AM) have recently emerged as being appropriate candidates for high-value engineered structures, including porous bio-implants and energy absorbing structures.
Eric Yang +13 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Marine Drugs, 2019 The small-spotted catshark is one of the most abundant elasmobranchs in the Northeastern Atlantic Ocean. Although its landings are devoted for human consumption, in general this species has low commercial value with high discard rates, reaching 100% in ...
María Blanco +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Rotatable Response Surface Designs for S1^n1 x S2^n2 Incorporating Neighbour Effects
Revstat Statistical JournalThis paper describes the response surface methodology for mixed-level factors of the form S1n1 x S2n2 when experimental units are affected by the adjacent neighbouring units.
Ashutosh Dalal +5 more
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Planning, analyzing and optimizing experiments [PDF]
Journal of Engineering Management and Competitiveness, 2020 Research and Development (R&D) encompasses all the innovative activities of organizations engaged in the development of new products (recycled materials, hardware, software, services) or enhancement of existing ones. In the US, the Research & Development
Popović Branko
doaj
Multi-Point, Multi-Objective Optimisation of Centrifugal Fans by 3D Inverse Design Method
International Journal of Turbomachinery, Propulsion and Power, 2023 In this paper, we present the design and optimization of a centrifugal fan with requirements of maximizing the total-to-static pressure rise and total-to-static efficiency at two operating points and the maximum torque provided by the motor power using a
Jiangnan Zhang, Mehrdad Zangeneh
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source