Results 41 to 50 of about 841,738 (326)
Rotatable Response Surface Designs for S1^n1 x S2^n2 Incorporating Neighbour Effects
Revstat Statistical JournalThis paper describes the response surface methodology for mixed-level factors of the form S1n1 x S2n2 when experimental units are affected by the adjacent neighbouring units.
Ashutosh Dalal +5 more
doaj +1 more source
Planning, analyzing and optimizing experiments [PDF]
Journal of Engineering Management and Competitiveness, 2020 Research and Development (R&D) encompasses all the innovative activities of organizations engaged in the development of new products (recycled materials, hardware, software, services) or enhancement of existing ones. In the US, the Research & Development
Popović Branko
doaj
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Zaštita Materijala, 2019 The present study compares the performances of the regression models developed by the response surface methodology combined with the full factorial, Box-Behnken or face central composite designs applied for the ultrasound-assisted KOH-catalyzed ...
Vlada B. Veljković +2 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Land, 2022 Surface mining for oil sand results in the formation of large pits that must be reclaimed. Some of these pits are backfilled with a myriad of substrates, including tailings rich in cations and anions, to form a solid surface.
Melissa House +3 more
doaj +1 more source
Prediction Variance Capabilities of Third-Order Response Surface Designs for Cuboidal Regions [PDF]
, 2021 Brenda Mbouamba Yankam +1 more
openalex +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source