Results 41 to 50 of about 449,892 (268)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Using ensemble climate projections to assess probabilistic hydrological change in the Nordic region [PDF]

open access: yesNatural Hazards and Earth System Sciences, 2011
Assessing hydrological effects of global climate change at local scales is important for evaluating future hazards to society. However, applying climate model projections to local impact models can be difficult as outcomes can vary considerably between ...
F. Wetterhall   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Bone tissue response to plasma-nitrided titanium implant surfaces

open access: yesJournal of Applied Oral Science, 2015
A current goal of dental implant research is the development of titanium (Ti) surfaces to improve osseointegration. Plasma nitriding treatments generate surfaces that favor osteoblast differentiation, a key event to the process of osteogenesis.
Emanuela Prado FERRAZ   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Affective response of postmenopausal women to resistance training on stable and unstable surfaces: a randomized cross-over study

open access: yesGeriatrics, Gerontology and Aging, 2023
Objective: To compare the affective response of postmenopausal women who undergo 6 weeks of resistance training on stable and unstable surfaces. Methods: This andomized counterbalanced cross-over study carried included 14 postmenopausal women (55 [SD, 3]
Danielle Cristhiane de Lira   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Efecto del etefón (ethrel) y el tiempo de almacenamiento sobre la maduración del plátano (Musa ABB cv. Harton) bajo refrigeración Effect of ethephon and storage time on ripening of plantain (Musa AAB cv Harton) under refrigeration

open access: yesBioagro, 2007
RESUMEN Se evaluó la maduración poscosecha del plátano luego de ser tratados con cinco dosis de etefón en el rango de concentración de 2000 a 6000 mg·L-1 de Ethrel, y almacenados por períodos comprendidos entre 24 y 240 horas.
Tony García   +4 more
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Seismic reliability analysis of soil slope based on Newmark sliding block model with representative slip surfaces and response surfaces

open access: yesEngineering Reports, 2023
This paper presents a framework combining Monte Carlo Simulation (MCS) and the Newmark sliding block model with representative slip surfaces (RSS) (model II) and multiple response surfaces method (MRSM) to conduct seismic reliability analysis and risk ...
Guangming Yu   +3 more
doaj   +1 more source

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