Results 111 to 120 of about 11,366,642 (301)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Pesticide Analytical and Response Center biennial report ...
, 2006 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Covers OCLC #1053901589, OCLC #1053901873None published 2002-
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 1962 Part of collection: Bruce Howard collection of photographs for Herald and Weekly Times, Melbourne, 1955-1995.; Title supplied by photographer, see acquisition file 204/09/00042.; Also available in an electronic version via the Internet at: http://nla.gov.
Howard, Bruce, 1936-
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Bruce Howard photographing building sites in Melbourne in 1955 [picture].
, 1955 Part of collection: Bruce Howard collection of photographs for Herald and Weekly Times, Melbourne, 1955-1995.; Title supplied by photographer, see acquisition file 204/09/00042.; Inscriptions: "Bruce Howard, Swanston St. building site, 1955."-- in ink on
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The car park and saddling paddock area at the Dajarra races, 1969 [picture] /
, 1969 Part of collection: Bruce Howard collection of photographs for Herald and Weekly Times, Melbourne, 1955-1995.; Title supplied by photographer, see acquisition file 204/09/00042.; "The course had been cleared from scrubland" -- File 204/09/00042.; Also ...
Howard, Bruce, 1936-
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source