Results 91 to 100 of about 5,192,011 (281)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Corrigendum: Towards an understanding of global brain data governance: ethical positions that underpin global brain data governance discourse

open access: yesFrontiers in Big Data, 2023
Paschal Ochang   +3 more
doaj   +1 more source

Reasserting Gija women's role in mine site reclamation: A perspective from the Argyle Diamond Mine

open access: yesJournal of Political Ecology
The Argyle diamond mine, in the East Kimberley region of Western Australia, ceased production in late 2020 after 37 years of operations and producing 865 million carats of rough diamonds.
Kia Dowell, Sarah Elizabeth Holcombe
doaj   +2 more sources

Professional Responsibility as a Lawyering Skill [PDF]

open access: yes, 1995
Little has been done to teach professional responsibility in a way that provides students with more than a mere sampling of rules and principles. In an attempt to move Beyond mere tinkering with the way professional responsibility is taught, Loyola Law ...
Wolfson, Michael E.
core   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Responsibility and the modern corporation [PDF]

open access: yes, 2018
Corporate governance crises as well as human rights issues in global value chains have pushed notions of Corporate Social Responsibility (CSR), Corporate Citizenship (CC), Triple P (People, Planet, Profit) and sustainable development onto the agenda of ...
Veldman, J.
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

The Corporate Social Responsibility Debate [PDF]

open access: yes, 2011
The purpose of this study is to evaluate the arguments concerning corporate social responsibility (CSR). The two sides of the debate are stakeholder theory and shareholder theory.
Cheers, Zachary
core   +1 more source

Home - About - Disclaimer - Privacy