Results 71 to 80 of about 1,451,435 (348)

Moving Forward with the Responsibility to Protect: Using Political Inertia to Protect Civilians [PDF]

open access: yes, 2014
First formulated in 2005, the Responsibility to Protect has emerged onto the international legal landscape. This doctrine recently was expressed in the 2011 United Nations-authorized humanitarian intervention in Libya.
Rose, Steven J.
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

African Solution to African Problems: AU and the Conflict Resolution in South Sudan

open access: yesPoliteja, 2018
The article deals with the concept of responsibility to protect, applied on the case study of South Sudan. The introductory part of the paper discusses the concept itself, its emergence and inclusion in relevant international law documents.
Kateřina Rudnicová
doaj   +1 more source

Upaya Dewan Keamanan Pbb Dalam Melindungi Rakyat Yaman Pada Revolusi Rakyat Yaman Tahun 2011 [PDF]

open access: yes, 2017
This research analyzes the implementation of the responsibility to protect the people of Yemen in the civil war by the UN Security Council. Since January 2011, Ali Abdullah Saleh forces have committed systematic and organized crimes against humanity to ...
Pakpahan, S. (Saiman)   +1 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The responsibility to protect as humanitarian negotiation: a space for the ‘politics of humanity’? [PDF]

open access: yes, 1980
This article first situates the Responsibility to Protect (RtoP) in relation to humanitarianism and the ‘politics of humanity’ through which common humanity is understood, negotiated and defended in response to ‘crises of humanity’.
Radice, Henry
core   +3 more sources

Responsible Veto Restraint: a Transitional Cosmopolitan Reform Measure for the Responsibility to Protect

open access: yesGlobal Responsibility to Protect, 2020
This article examines reform to the ‘veto’ power held by the five permanent members of the United Nations Security Council. The responsibility to react to mass atrocity crimes under the Responsibility to Protect (R2P) lies predominantly in the hands of ...
R. Illingworth
semanticscholar   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

The Transatlantic Dimension to the Conflict in Lebanon: Whatever Happened to the Responsibility to Protect? [PDF]

open access: yes, 2006
In this BASIC Paper, Dr. Ian Davis examines the U.S. and U.K. roles and responsibilities in the Lebanon conflict. He supports the call being made by many governments and civil society groups: that a political solution to the twin crises of Lebanon and ...
Ian Davis
core  

The responsibility to protect and the use of force: remaking the procrustean bed? [PDF]

open access: yes, 2015
The emergence of the Responsibility to Protect (R2P) owed much to the need to enhance the UN’s ability to act forcibly in the face of the most extreme cases of gross human suffering.
Annan K   +24 more
core   +2 more sources

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