Results 41 to 50 of about 1,289,107 (310)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Ward housekeepers in mental health environments [PDF]

open access: yes, 2007
Purpose – In the year 2000, the UK Government promoted the concept that hospital services be shaped around the needs of the patient to make their stay in hospital as comfortable as possible.
May, D., Suckley, Louise
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

On the Job: Eleanor Fitzpatrick, RN, MSN, CCRN [PDF]

open access: yes, 2013
Eleanor “Elly” Fitzpatrick joined Jefferson in 1987 as a clinical nurse specialist. Initially serving in the Intermediate Surgical Intensive Care Unit (ISICU), she soon became clinical nurse specialist for the Surgical ICU (SICU), as well.

core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Sądowa ochrona samodzielności finansowej jednostek samorządu terytorialnego przed rozstrzygnięciami nadzorczymi regionalnych izb obrachunkowych

open access: yesOpolskie Studia Administracyjno-Prawne, 2019
Financial independence of territorial self-government units means performing important public tasks in the field of financial management on their own behalf and with their own responsibility in terms of aspects related to income and expenditure, and ...
Jadwiga Glumińska-Pawlic
doaj   +1 more source

Reflections on the Practicality of Good Theory [PDF]

open access: yes, 2004
Jennifer Kennison noticed something different about the way her high school chemistry students were working together during Complex Instruction rotation. Her attention to the change in her students’ learning caused me to think about how Elizabeth Cohen’s
Brodeur, Bethany   +2 more
core   +1 more source

Policy and service responses to rough sleeping among older people [PDF]

open access: yes, 2000
Rough sleeping in Britain has a long history, and interventions have alternated between legal sanctions and humanitarian concern. This paper critically examines recent changes in homeless policies and services, with particular reference to the needs of ...
Crane, M., Warnes, A.M.
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Walking the Walk: The Case for Internal Equity, Diversity, and Inclusion Work Within the Canadian Public Health Sector

open access: yesHealth Equity, 2019
Equity is fundamental to public health practice. However, limited work has evaluated public health units, as employers, in ensuring equitable workplaces.
Ankur Shahi   +2 more
doaj   +1 more source

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