Results 61 to 70 of about 268,248 (309)

The Problem of Imposing the Duty to Improve Neighborhoods in Municipal Units

open access: yesVestnik Omskoj Ûridičeskoj Akademii, 2015
The authors of this research paper by analyzing judicial practice reveal the problems faced by municipal units in the field of neighborhood improvement. The authors conclude that municipal units are empowered to establish responsibility for cleaning the ...
Rashidov Ye. F., Chulkov Yu. P.
doaj  

Program to Promote Personal and Social Responsibility in the Secondary Classroom

open access: yesFrontiers in Psychology, 2017
The performance of school children has been studied by considering partial relationships between several personal variables such as the link between cognition and motivation.
Miguel A. Carbonero   +3 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Quantifying the national responsibilities for the conservation of transboundary migratory species Siberian ibex

open access: yesEcological Indicators
Transboundary conservation is critical to halting global biodiversity loss, yet transboundary species represent a particular challenge in terms of who is primarily responsible for their conservation and how to coordinate between range states.
Jingwen Xu   +15 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Designing Reverse Logistics Network with a Social Approach to Recycle Great household Waste under Uncertainty Conditions

open access: yesJournal of Applied Research on Industrial Engineering, 2015
The importance of social responsibility in organizational and business units have been increasingly stressed by the researchers in recent years.
Atefeh Salimi   +2 more
doaj  

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