Results 51 to 60 of about 270,398 (260)
THE EFFECT OF FINANCIAL PERFORMANCE AND GOOD CORPORATE GOVERNANCE ON FIRM VALUE MODERATED BY CORPORATE SOCIAL RESPONSIBILITY VARIABLES ON THE INDONESIAN STOCK EXCHANGE [PDF]
Eurasia: Economics & Business, 2023 The development of the world in the current era of globalization is accompanied by competitive business competition. Companies try to place themselves in a stable and competitive position to survive and develop.
Widiasih N.L.P.S., Wiagustini N.L.P.
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Problem of Imposing the Duty to Improve Neighborhoods in Municipal Units
Vestnik Omskoj Ûridičeskoj Akademii, 2015 The authors of this research paper by analyzing judicial practice reveal the problems faced by municipal units in the field of neighborhood improvement. The authors conclude that municipal units are empowered to establish responsibility for cleaning the ...
Rashidov Ye. F., Chulkov Yu. P.
doaj
Jurnal Perspektif Pembiayaan dan Pembangunan Daerah, 2018 This study aims to analyze the effect of firm characteristics of corporate social responsibility disclosure. The population in this study is as many as 143 companies listed in the Indonesia Sharia Stock Index, whereas units of analysis in this study were
Ahmad Rifani Irham +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
تشكيل واجهات المجمعات السكنية واثره في المشهد الحضري لمدينة بغداد [PDF]
Engineering and Technology Journal, 2008 The selection of this research ,was based on the following facts:- The deformation that tookplace in the formal relationships for the residential complexes inBaghdad due to many factors such as: political, economical, social and other factors.
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source