Results 71 to 80 of about 2,414,155 (290)

تشكيل واجهات المجمعات السكنية واثره في المشهد الحضري لمدينة بغداد [PDF]

Engineering and Technology Journal, 2008
The selection of this research ,was based on the following facts:- The deformation that tookplace in the formal relationships for the residential complexes inBaghdad due to many factors such as: political, economical, social and other factors.
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Quantifying the national responsibilities for the conservation of transboundary migratory species Siberian ibex

Ecological Indicators
Transboundary conservation is critical to halting global biodiversity loss, yet transboundary species represent a particular challenge in terms of who is primarily responsible for their conservation and how to coordinate between range states.
Jingwen Xu, Yingying Zhuo, Sabina Koirala, Muhammad Zafar Khan, Shamshidin Abduriyim, Chagsaldulam Odonjavkhlan, Vladislav Vinogradov, Ruidong Zhang, Baolin Zhang, Kathreen Ruckstuhl, António Alves da Silva, Joana Alves, Alice Hughes, Jiajia Liu, Muyang Wang, Weikang Yang   +15 more
doaj   +1 more source

Program to Promote Personal and Social Responsibility in the Secondary Classroom

Frontiers in Psychology, 2017
The performance of school children has been studied by considering partial relationships between several personal variables such as the link between cognition and motivation.
Miguel A. Carbonero, Luis J. Martín-Antón, Lourdes Otero, Eugenio Monsalvo   +3 more
doaj   +1 more source

Intangibles, Global Networks & Corporate Social Responsibility [PDF]

Network organisations emphasise the importance of corporate and product intangible assets. In global competition, the managerial economics of intangibles imposes new network policies of corporate social responsibility, dominated by global social issues ...
Silvio M. Brondoni
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

The structural contradictions and constraints on corporate social responsibility: Challenges for corporate social irresponsibility [PDF]

, 2012
Purpose - This chapter engages critically with the ideas of corporate social responsibility (CSR) and irresponsibility (CSI) in order to examine their utility for the purposes of realizing more socially just and environmentally sustainable social and ...
Nunn, Alex, Nunn, A.; id_orcid, Nunn, A, Alex Nunn   +3 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

The degree of the social worker's application of social responsibility and its relationship to enhancing the quality of services in orphan care institutions

Journal of Umm Al-Qura University for Educational and Psychological Sciences
The study aimed to: identify the degree of social workers’ application of social responsibility (religious and ethical responsibility, personal responsibility, societal responsibility, and national responsibility) in orphan care institutions; explore the
Kholoud bint Saad bin Abdulaziz Al-Yousef
doaj   +1 more source