Results 111 to 120 of about 3,686,228 (287)

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Adoption of voluntary sustainability standards in Australia's agri-food systems: primary producers' challenges and opportunities

Cleaner and Responsible Consumption
As awareness of the environmental and social impacts of agri-food systems grows, the adoption of voluntary sustainability standards (VSS) is promoted to encourage sustainable farming practices. However, the adoption of VSS remains limited.
Francesco Tacconi, Peggy Schrobback, Enayat A. Moallemi   +2 more
doaj   +1 more source

Do they know its CSR at all? An exploration of socially responsible music consumption

, 2016
The increasing visibility and elevated status of musicians has become prominent in contemporary society as a consequence of technological advances and the development of both mass and specialized targeted audiences. Consequently, the actions of musicians
Tinson, Julie, Green, Todd, Sinclair, Gary   +2 more
core   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Health, Habits and Responsible and Sustainable Consumption

[EN] Natural resources are essential for human well-being, quality of life and health. Current consumption of these resources is disproportionate, with a markedly commercial character. The need arises to change the current paradigm of consumption towards
García Fernández, Rubén, Martín Vázquez, Cristian, Calvo Ayuso, Natalia, Marqués Sánchez, Pilar, Pinto Carral, Arrate, Martínez Fernández, María Cristina   +5 more
core  

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Plant proteins for human consumption – from local to global opportunities and challenges in a full value chain context

Cleaner and Responsible Consumption
Environmental concerns together with a growing global population and health benefits call for an increased use of plant proteins in the human diet. This review paper summarizes opportunities and challenges of such an increased use and reveals the way ...
Eva Johansson, Georg Carlsson, Åsa Grimberg, William R. Newson, Thomas Prade, Sara Spendrup, Sven-Erik Svensson   +6 more
doaj   +1 more source

Survey data on household finance and consumption - research summary and policy use [PDF]

The first part of this paper provides a brief survey of the recent literature that employs survey data on household finance and consumption. Given the breadth of the topic, it focuses on issues that are particularly relevant for policy, namely i) wealth ...
The Eurosystem Household Finance and Consumption Network
core  

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Everyday circular literacy in Singaporean households: Informal relational pedagogies in teaching and learning about circular R-behaviours

Cleaner and Responsible Consumption
Despite the state's emphasis on formal environmental education, informal settings for fostering circular literacy cannot be understated. Whereas environmental literacy has been well researched in the literature, circular literacy, which involves teaching/
Qian Hui Tan, Brenda Yeoh
doaj   +1 more source