Results 31 to 40 of about 25,873 (260)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Aceh is a province located in the western part of Indonesia, and most of its region is a coastal area that faces rapid population growth, which puts pressure on sectors like fisheries and marine resources.
M.A. Chaliluddin +7 more
doaj +1 more source
Responses of coastal fishery resources to rapid environmental changes
AbstractCoastal systems experience strong impacts of ongoing environmental change, affecting fish communities and subsequently fishery yields. In the Baltic Sea, the combined effects of climate‐induced changes and eutrophication‐related pressures constitute major threats to its living resources.
Weigel, Benjamin, Peltonen, Heikki
openaire +5 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The coastal fisheries sector in Sri Lanka is crucial for food security and nutrition, employment creation, poverty reduction, and foreign exchange earnings.
R.A.D.S. RANATUNGA +3 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Following years of preparatory efforts and evaluation, China formally acceded to the Agreement on Port State Measures to Prevent, Deter and Eliminate Illegal, Unreported and Unregulated Fishing (PSMA) on April 16, 2025, marking a new advancement in its ...
Xidi Chen, Lei Wang
doaj +1 more source
A misalignment between the legislation and the effectiveness of Mediterranean fisheries management has emerged due to the status of the stocks (still largely in overfishing) and the discontent of stakeholders regarding management plans and tools that are
Loretta Malvarosa +11 more
doaj +1 more source

