Results 91 to 100 of about 3,537,691 (295)

Physician versus patient use of AI for diabetes prevention: public perceptions and comfort levels

Frontiers in Digital Health
BackgroundType 2 diabetes is a major public health challenge that can often be prevented through lifestyle interventions. Artificial intelligence (AI) is increasingly used for risk prediction, behavioral coaching, and individualized prevention, offering ...
Gloria Maria Carmona Clavijo, Paige Nong, Sean Tan, Jodyn Platt   +3 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Academic institutional entrepreneurs in Germany: navigating and shaping multi-level research commercialization governance

Triple Helix, 2018
Resumen Usando archivos institucionales y entrevistas con investigadores y administradores en el estado alemán de Renania del Norte-Westfalia, encontramos que los administradores deciden la profundidad de su relación con los investigadores basados en el ...
Liudvika Leišytė, Lisa Sigl
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Responsible innovation in public policy: Compulsory banking of the elderly in Argentina

Trilogía Ciencia Tecnología Sociedad, 2015
since March 2012, Argentine retirees and pensioners receive their salaries through a savings bank compulsorily, according to the provisions of a law passed in October 2011 (regulated by the Central Bank of Argentine
Adriana Fassio, Javier Ignacio García Fronti   +1 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Ensuring Responsible Nanotechnology Innovation

NanoEthics
The challenge of considering the ethical, environmental, economic, social, legal and cultural (E3LSC) dimensions of nanotechnology innovation is of enduring and increasing importance for societies worldwide.
Jianni Tien, Katherine Kenny, Alex Broom, Alice Motion, Stephen Bartlett   +4 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Responsible Innovation in light of Levinas: rethinking the relation between responsibility and innovation [PDF]

Journal of Responsible Innovation, 2017
To date, much of the work on Responsible Innovation (RI) has focused on the ‘responsible’ part of RI. This has left the ‘innovation’ part in need of conceptual innovation of its own. If such conceptual innovation is to contribute to a coherent conception of RI, however, it is crucial to better understand the relation between responsibility and ...
openaire   +4 more sources