Results 111 to 120 of about 1,193,547 (261)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Developing an Index to Measure the Value of Health Care Provided to Stroke Patients

open access: yesAnnals of Indian Academy of Neurology
Background and Objectives: It is possible to evaluate health services for stroke patients based on clinical benefits. However, in recent years, questions about responsiveness and outcomes have also emerged.
Halil Şengül   +3 more
doaj   +1 more source

Development and initial validation of the ibadan knee/hip osteoarthritis outcome measure

open access: yesSouth African Journal of Physiotherapy, 2007
Background and Aim: Development of outcome measures remains a focus of health research in the 21st century. Outcome measures originally developed for the Nigerian environment are very rare.
A. O. Akinpelu   +3 more
doaj   +1 more source

Financial Incentives and the Timing of Retirement: Evidence from Switzerland [PDF]

open access: yes
We use reforms in the Swiss public retirement system to identify the responsiveness of retirement timing to financial incentives. A permanent reduction of retirement benefits by 3.4 percent induces more than 70 percent of females to postpone their ...
Barbara Hanel, Regina Riphahn
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Patient satisfaction analysis on service quality of dental health care based on empathy and responsiveness

open access: yesDental Research Journal, 2011
Background: Transformation of health care is underway from sellers′ market to consumers′ market, where the satisfaction of the patients′ need is a primary concern while defining the service quality. Hence, commitment to provide a high-quality service and
Fellani Danasra Dewi   +2 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Analisis Pengaruh Kualitas Layanan Terhadap Kepuasan Pelanggan Servis Truk Di Toko Gemilang Motor Palembang [PDF]

open access: yes, 2016
This research aims to analyze the influence between the quality of service that consists of 5 dimensions of service quality: tangible, reliability, responsiveness, assurance, and emphaty toward customer satisfaction service truck in Toko Gemilang ...
David, Leo
core  

Response to Responses [PDF]

open access: yesModernist Cultures, 2017
Kindellan, M.R., Kotin, J.
openaire   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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