Results 81 to 90 of about 1,193,547 (261)
B-1 Cell Heterogeneity and the Regulation of Natural and Antigen-Induced IgM Production. [PDF]
, 2016 A small subset of B cells, termed B-1 cells, with developmental origins, phenotypes, and functions that are distinct from those of conventional B cells exist in mice. It contributes the vast majority of spontaneously produced "natural" IgM.
Alugupalli +85 more
core +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Sensitiveness of the Constant-Murley’s Shoulder and Quick DASH as an Outcome Measure for Midshaft Clavicle Fracture [PDF]
Malaysian Orthopaedic Journal, 2010 BACKGROUND: Quick DASH and Constant-Murley’s Shoulder are two valid measuring tools for health status and are useful for patients with a wide variety of upper-extremity complaints; it is sufficiently sensitive to reveal even small changes in function ...
R Magetsari
doaj
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Weaving webs of connection: Empathy, perspective taking, and students’ motivation [PDF]
, 2019 L2 motivation is a relational phenomenon, shaped by teacher responsiveness (Lamb, 2017; Ushioda, 2009). Little, however, is known about the practices in which responsiveness is manifested.
Henry, Alastair, Thorsen, Cecilia
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
LA CALIDAD DE LA DEMOCRACIA PARAGUAYA: UN AVANCE SOBRE CAMINOS TORTUOSOS
América Latina Hoy, 2010 En el marco de una preocupación cada vez mayor por analizar la calidad de las nuevas democracias, este artículo se ocupa de examinar el caso de Paraguay.
Mikel BARREDA, Marc BOU
doaj
Learning a musical instrument: the influence of interpersonal interaction on outcomes for school-aged pupils [PDF]
, 2011 Researchers in recent years have increasingly placed an emphasis on seeking pupils' perceptions of educational settings. Alongside this shift towards attaching value to the pupil viewpoint has been a growing interest concerning how interpersonal ...
Creech, Andrea, Hallam, Susan
core +2 more sources
Differential Tissue Response to Growth Hormone in Mice [PDF]
, 2018 Growth hormone (GH) has been shown to act directly on multiple tissues throughout the body. Historically, it was believed that GH acted directly in the liver and only indirectly in other tissues via insulin‐like growth hormone 1 (IGF‐1).
Banerjee, Ronadip R. +4 more
core +2 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source