Results 1 to 10 of about 3,414 (110)
Frontiers in Molecular Biosciences, 2021 Disintegrins are small cysteine-rich proteins found in a variety of snake venom. These proteins selectively modulate integrin function, heterodimeric receptors involved in cell-cell and cell-matrix interaction that are widely studied as therapeutic ...
Ariana A. Vasconcelos +7 more
doaj +1 more source
(Bio)Functionalisation of Metal–Organic Polyhedra by Using Click Chemistry
Chemistry – A European Journal, Volume 29, Issue 60, October 26, 2023., 2023 Copper(I)‐catalysed alkyne‐azide cycloaddition click chemistry is a versatile post‐synthetic tool to functionalize the surface chemistry of alkyne‐functionalized cuboctahedral Metal–Organic Polyhedra (MOPs). This methodology enables quantitative functionalization of MOPs with a wide range of functional groups, including polymers, carboxylic and ...
Laura Hernández‐López +8 more
wiley +1 more source
Synthese von C60/[10]CPP‐Catenanen durch Regioselektive Nanokapsel‐Templierte Bingel Bis‐Addition
Angewandte Chemie, Volume 135, Issue 42, October 16, 2023., 2023 Die Kombination von drei Methoden (Tether, Nanohoop‐Template und supramolekulare Schattenmaske) ermöglichte die itero‐ und regioselektive Synthese von [2]Catenanen durch Bis‐Addition von Bis‐Bromomalonaten an den Komplex C60⸦[10]CPP. Die Verwendung einer „spurlosen“ Nanokapsel‐Schattenmaske war der Schlüssel für eine 87 %ige Selektivität für das „in ...
Fabian M. Steudel +7 more
wiley +1 more source
Hipotensão intracraniana espontânea.
Acta Médica Portuguesa, 2001 The authors consider some clinical and radiological aspects of spontaneous intracranial hypotension syndrome, based on the knowledge obtained from three clinical situations. Postural headache was a constant complaint.
J Graça +5 more
doaj +1 more source
Synthesis of C60/[10]CPP‐Catenanes by Regioselective, Nanocapsule‐Templated Bingel Bis‐Addition
Angewandte Chemie International Edition, Volume 62, Issue 42, October 16, 2023., 2023 The combination of three approaches (tether, nanohoop template & supramolecular shadow mask) enabled the itero‐ and regioselective synthesis of [2]catenanes via bis‐addition of bis‐bromomalonates to the complex C60⸦[10]CPP. The use of a “traceless” nanocapsule shadow mask was key for obtaining 87 % selectivity for the “in,out‐trans‐3′′ product, where ...
Fabian M. Steudel +7 more
wiley +1 more source
Glifosato: um problema da ciência e da tecnologia para a sociedade
Indagatio Didactica, 2019 Numa definição inicial - sempre é possível se complexificar as definições - podemos dizer que a Química é a ciência que estuda as substâncias, suas transformações e as energias envolvidas nelas. Daí depreende-se que o conceito de Reação Química é central
Andressa Kuhnen Silva +4 more
doaj +1 more source
A Polymeric Nanoparticle Formulation for Targeted mRNA Delivery to Fibroblasts
Advanced Science, Volume 10, Issue 5, February 14, 2023., 2023 Messenger RNA (mRNA) is a promising tool to deliver therapeutic proteins in many diseases, including fibrotic disorders. Here, a polymeric nanoparticle formulation is developed after high‐throughput screening of 152 polymers in a fibroblast model.
Artur Filipe Rodrigues +6 more
wiley +1 more source
Acta Médica Portuguesa, 2001 The increasing use of magnetic resonance imaging (MRI) in fetal evaluation is due to its excellent structural and morphological resolution. We report nine fetal MRI examinations and discuss some of the technical issues related to this technique.We report
P Vilela, J Duarte, A Goulão
doaj +1 more source
NMR in Biomedicine, Volume 36, Issue 2, February 2023., 2023 18O‐enrichment of liver glycogen, triglyceride glycerol, and blood glucose of mice given 18O‐water during overnight feeding was quantified by 13C NMR and MS. Glycogen 18O‐enrichment of oxygens 3, 5, and 6 from isotope‐shifted 13C signals informed indirect pathway contributions from different sources.
Margarida Coelho +11 more
wiley +1 more source
Estudo por ressonância magnética do fluxo aquedutal em doentes com hidrocefalia pressão normal.
Acta Médica Portuguesa, 2001 The treatment of patients with the so-called Normal Pressure Hydrocephalus (NPH) consists of ventricular shunting, but only in some cases is there clinical improvement.
S Matias +4 more
doaj +1 more source