Results 21 to 30 of about 1,453,291 (153)

Synthesis of C60/[10]CPP‐Catenanes by Regioselective, Nanocapsule‐Templated Bingel Bis‐Addition

Angewandte Chemie International Edition, Volume 62, Issue 42, October 16, 2023., 2023
The combination of three approaches (tether, nanohoop template & supramolecular shadow mask) enabled the itero‐ and regioselective synthesis of [2]catenanes via bis‐addition of bis‐bromomalonates to the complex C60⸦[10]CPP. The use of a “traceless” nanocapsule shadow mask was key for obtaining 87 % selectivity for the “in,out‐trans‐3′′ product, where ...
Fabian M. Steudel, Ernest Ubasart, Luigi Leanza, Míriam Pujals, Teodor Parella, Giovanni M. Pavan, Xavi Ribas, Max von Delius   +7 more
wiley   +1 more source

A Polymeric Nanoparticle Formulation for Targeted mRNA Delivery to Fibroblasts

Advanced Science, Volume 10, Issue 5, February 14, 2023., 2023
Messenger RNA (mRNA) is a promising tool to deliver therapeutic proteins in many diseases, including fibrotic disorders. Here, a polymeric nanoparticle formulation is developed after high‐throughput screening of 152 polymers in a fibroblast model.
Artur Filipe Rodrigues, Catarina Rebelo, Susana Simões, Cristiana Paulo, Sónia Pinho, Vítor Francisco, Lino Ferreira   +6 more
wiley   +1 more source

Enrichment of hepatic glycogen and plasma glucose from H₂18O informs gluconeogenic and indirect pathway fluxes in naturally feeding mice

NMR in Biomedicine, Volume 36, Issue 2, February 2023., 2023
18O‐enrichment of liver glycogen, triglyceride glycerol, and blood glucose of mice given 18O‐water during overnight feeding was quantified by 13C NMR and MS. Glycogen 18O‐enrichment of oxygens 3, 5, and 6 from isotope‐shifted 13C signals informed indirect pathway contributions from different sources.
Margarida Coelho, Rohit Mahar, Getachew D. Belew, Alejandra Torres, Cristina Barosa, Fernando Cabral, Ivan Viegas, Amalia Gastaldelli, Vera M. Mendes, Bruno Manadas, John G. Jones, Matthew E. Merritt   +11 more
wiley   +1 more source

Unravelling the Mechanistic Pathway of the Hydrogen Evolution Reaction Driven by a Cobalt Catalyst

Angewandte Chemie, Volume 134, Issue 40, October 4, 2022., 2022
A CoI complex bearing a redox‐active κ‐N3P2 pentadentate ligand and its activity towards hydrogen evolution reaction is reported in this work. A combination of spectroscopic, electrochemical and computational techniques is employed to characterize the intermediate species, demonstrating an unusual homolytic coupling reaction pathway between two ...
Bing Jiang, Marcos Gil‐Sepulcre, Pablo Garrido‐Barros, Carolina Gimbert‐Suriñach, Jia‐Wei Wang, Jordi Garcia‐Anton, Pau Nolis, Jordi Benet‐Buchholz, Nuria Romero, Xavier Sala, Antoni Llobet   +10 more
wiley   +1 more source

Characterization data and kinetic studies of novel lipophilic analogues from 2,4-dichlorophenoxyacetic acid and Propanil herbicides

Data in Brief, 2020
This work describes the data collection of new lipophilic esters and amides herbicides, analogues to 2,4-dichlorophenoxyacetic acid (2,4-D) and Propanil.
Larissa M. Porciuncula, Alex R. Teixeira, Maria F.C. Santos, Marcelo G.M. D'Oca, Elisa S. Orth, Caroline R.M. D'Oca   +5 more
doaj   +1 more source

Amide hydrogens reveal a temperature-dependent structural transition that enhances site-II Ca2+-binding affinity in a C-domain mutant of cardiac troponin C

Scientific Reports, 2017
The hypertrophic cardiomyopathy-associated mutant D145E, in cardiac troponin C (cTnC) C-domain, causes generalised instability at multiple sites in the isolated protein.
Tiago Veltri, Guilherme A. P. de Oliveira, Ewa A. Bienkiewicz, Fernando L. Palhano, Mayra de A. Marques, Adolfo H. Moraes, Jerson L. Silva, Martha M. Sorenson, Jose R. Pinto   +8 more
doaj   +1 more source

Estudo químico de Derris negrensis [PDF]

Acta Amazonica, 1976
Resumo Identifica-se por metodologia físico-química, cromatografia em coluna (CC) e camada delgada (CCD) e espectrometrias no infravermelho (IV), no ultravioleta (UV) e de ressonância magnética nuclear (RMN), a presença de rotenona (28,5%) e ...
M. N. Lima Vasconcelos, J. G. Soares Maia   +1 more
doaj   +1 more source

Mechanistic Insights and Catalytic Efficiency of a 2,2'-Bipyridine-Coordinated Peroxidovanadium Complex as a Haloperoxidase Biomimetic. [PDF]

Chempluschem
A peroxidovanadium(V) complex mimics vanadium haloperoxidases for eco‐friendly halogenation of organic substrates. Density functional theory studies reveal two major reaction pathways for iodide/bromide oxidation. The catalyst offers high‐yield bromination/iodination of 8‐hydroxyquinoline (73/86%) under mild conditions (30 °C, pH 5.8), and it also ...
Fachini LG, Elisandro EVS, Baptistella GB, Bottini RCR, Briganti M, Nunes GG, de Sá EL.   +6 more
europepmc   +2 more sources

Ressonância nuclear magnética no diagnóstico de pseudoaneurisma de ventrículo esquerdo. Antigo problema, nova opção [PDF]

Arquivos Brasileiros de Cardiologia, 1997
Paciente feminina, 67 anos, internada por infarto agudo do miocárdio de parede lateral, com edema agudo de pulmão e evolução para choque cardiogênico nas primeiras horas.
Glaura S. Alvarenga, Liliane Kopel, Luís Alberto Oliveira Dallan, Luiz Francisco Avila, Maristela C. Monachini, Silvia G. Lage   +5 more
doaj   +1 more source

A FÍSICA NA RESSONÂNCIA MAGNÉTICA

Conexões: Ciência e Tecnologia, 2020
O presente trabalho teve como objetivo principal promover a divulgação dos conceitos físicos envolvidos na formação de imagens através da Ressonância Magnética (RM).
JOSÉ CARLOS FERREIRA BASTOS, Gilvandenys Leite Sales, Darkson Fernandes da Costa   +2 more
doaj   +1 more source