Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries [PDF]
, 2011 <p><b>Objective:</b> We have previously demonstrated that bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs), is effective in reducing neointimal formation in rodent models of vascular injury by reducing smooth ...
Baker, A.H. +10 more
core +1 more source
Circulation: Cardiovascular Interventions, 2011 In the past decade, tremendous progress has been made in reducing the incidence of restenosis with the advent of the drug-eluting stent (DES). With “plain old balloon angioplasty,” rates of acute and chronic vessel occlusion were unacceptably high at ≈30% to 60%, secondary to acute and chronic recoil and constrictive remodeling.
Bill D. Gogas +2 more
openaire +4 more sources
Uncertainty quantification of a three-dimensional in-stent restenosis model with surrogate modelling [PDF]
arXiv, 2021 In-Stent Restenosis is a recurrence of coronary artery narrowing due to vascular injury caused by balloon dilation and stent placement. It may lead to the relapse of angina symptoms or to an acute coronary syndrome. An uncertainty quantification of a model for In-Stent Restenosis with four uncertain parameters (endothelium regeneration time, the ...
arxiv
Use of Nuclear Magnetic Resonance Imaging Angiography to Follow-Up Arterial Remodeling in an Animal Model [PDF]
, 1998 Appropriately sized arteries in small animals may be possible models for studying the remodeling process as occurs after arterial balloon injury in humans. Magnetic resonance imaging (MRI) is able to noninvasively image tissue in vivo.
Berthold Höfling +9 more
core +1 more source
Stent-in-Stent Endovascular Correction in Right Internal Carotid Artery Restenosis: a Clinical Case
Креативная хирургия и онкология, 2021 Background. Carotid artery restenosis is a rare complication of carotid stenting. The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) reveals an in-stent restenosis rate of 0–6 %, a fairly low value given an extensive study ...
T. N. Khafizov +6 more
doaj +1 more source
Flexible composition and execution of high performance, high fidelity multiscale biomedical simulations [PDF]
Interface Focus April 6, 2013 3 2 20120087, 2012 Multiscale simulations are essential in the biomedical domain to accurately model human physiology. We present a modular approach for designing, constructing and executing multiscale simulations on a wide range of resources, from desktops to petascale supercomputers, including combinations of these.
arxiv +1 more source
Angiotensin-converting enzyme insertion/deletion polymorphism does not influence the restenosis rate after coronary stent implantation [PDF]
, 2002 Background. Experimental studies have shown an activation of the angiotensin-converting enzyme (ACE) system as a response to endothelial injury. Recent publications have elucidated the hypothesis that the ACE gene polymorphism may influence the level of ...
de Jaegere, Peter +10 more
core +1 more source
Российский кардиологический журнал, 2019 Aim. To identify the effect of preprocedural laboratory parameters on the occurrence of in-stent restenosis in various types of stents, to assess the significance of gender, age and various forms of coronary artery disease (CAD) as risk factors for ...
D. V. Shames +3 more
doaj +1 more source
A multiphysics modeling approach for in-stent restenosis: Theoretical aspects and finite element implementation [PDF]
arXiv, 2022 Development of in silico models are intrinsic in understanding disease progression in soft biological tissues. Within this work, we propose a fully-coupled Lagrangian finite element framework which replicates the process of in-stent restenosis observed post stent implantation in a coronary artery.
arxiv
Layer-by-layer biofabrication of coronary covered stents with clickable elastin-like recombinamers [PDF]
, 2019 Producción CientíficaCoronary artery disease is the leading cause of death around the world. Endovascular stenting is the preferred treatment option to restore blood flow in the coronary arteries due to the lower perioperative morbidity when compared ...
Fernández Colino, Alicia +7 more
core +2 more sources