Results 121 to 130 of about 285,581 (295)

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

open access: yesAdvanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao   +7 more
wiley   +1 more source

THE RELATIONSHIP BETWEEN THE DEFAULT MODE RESTING STATE NEURAL NETWORK, RESPIRATORY SINUS ARRHYTHMIA, AND SELF-FOCUSED COGNITION: AN EMPIRICAL ANALYSIS [PDF]

open access: yes, 2013
Functional activity within the default mode resting state neural network (RSNN) and the resting respiratory sinus arrhythmia (RSA) may represent an integrated neural and peripheral cardiovascular index of the baseline, resting state in humans.
Egizio, Victoria
core  

Resting-state network organisation in children with traumatic brain injury

open access: yes, 2022
Resting-state network organisation in children with traumatic brain ...
M Königs (13309032)   +6 more
core  

Enzyme‐Linked Cycloaddition Assay (ELCA) for Rapid, Ultra‐Sensitive Monitoring of Secreted Sialoglycoproteins

open access: yesAdvanced Science, EarlyView.
Secreted glycoproteins report on cellular state faster than the cell surface, yet remain hard to measure. The Enzyme‐Linked Cycloaddition Assay (ELCA) combines metabolic azide labeling with click chemistry in an ELISA‐like microplate format, resolving sialylation changes within minutes for 1‐2 EUR per sample.
Jon Lundstrøm   +2 more
wiley   +1 more source

Digital mucous cyst – case report

open access: yes, 2014
Introduction . Digital mucous cyst is a benign, translucent nodule that occurs on the dorsum of the finger. The cyst is filled with a gelatinous mass and connected with the interphalangeal joint. Arthritis plays the main role in the etiology. Objective
Jadwiga Sierocińska-Sawa   +5 more
core   +1 more source

A Biomimetic PLK1 Nanodelivery System Promotes Migrasome‐Mediated Mitocytosis to Restore Efferocytosis and Functional Recovery After Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
MM‐NPs@PLK1 are formed by encapsulating PLK1 plasmids within CBP5 and coating the nanocomplexes with macrophage membranes. After macrophage‐associated uptake, the NPs@PLK1 enter the cytoplasm and release the PLK1‐encoding plasmid in response to elevated intracellular ROS levels.
Zhenxin Hu   +13 more
wiley   +1 more source

Apical Cyst Theory: a Missing Link

open access: yesDental Hypotheses, 2010
Introduction: The mechanism of the formation of apical cyst has been elusive. Several theories have long been proposed and discussed speculating how an apical cyst is developed and formed in the jaw bone resulting from endododontic infection. Two popular
George T.-J. Huang
doaj  

XChrom: A Cross‐Cell Chromatin Accessibility Prediction Model Integrating Genomic Sequence and Cellular Context

open access: yesAdvanced Science, EarlyView.
XChrom is a deep learning framework that integrates genomic sequence and single‐cell context to predict chromatin accessibility. It generalizes to unseen cells and genomic regions, enabling cross‐sample and cross‐species analysis. Applied to COVID‐19 patient data, XChrom reveals key transcriptional regulatory mechanisms and disease‐associated ...
Yuanyuan Miao   +5 more
wiley   +1 more source

Distribution of Resting Cysts of Gonyaulax tamarensis var. excavata and Shellfish Toxicity

open access: yes, 1983
Our objective was to determine whether intertidal dinoflagellate resting cyst distributions might be useful for determining areas which should be closely monitored for toxins in shellfish. Gonyaulax tamarensis var. excavata cyst distributions in Gulf of
J. W. Hurst   +4 more
core   +1 more source

Early Endoscopic Repair of Traumatic Skull Base Dural Injuries: Challenging the Dogma of Conservative Management

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Traditional management of traumatic skull base dural injury has often favored observation and conservative therapy, despite the risk of delayed intracranial complications. This paradigm originated when operative intervention required craniotomy and carried significant morbidity.
Jessica W. Grayson   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy