Results 101 to 110 of about 285,581 (295)

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

open access: yesAdvanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu   +9 more
wiley   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

open access: yesHepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam   +10 more
wiley   +1 more source

Cyst-theca relationship, life cycle and effects of temperature and salinity on cyst morphology of Gonyaulax baltica sp. nov. (Dinophyceae) from the Baltic Sea area

open access: yes, 2002
A new species of Gonyaulax, here named Gonyaulax baltica sp. nov., has been isolated from sediment samples from the southeastern Baltic. Culture strains were established from individually isolated cysts, and cyst formation was induced in a nitrogen ...
Marianne Ellegaard   +9 more
core   +1 more source

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

open access: yesAdvanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu   +14 more
wiley   +1 more source

Resting stage in the biogenic fraction of surface sediments from the deep Mediterranean Sea

open access: yesScientia Marina, 2004
The presence of resting stages in neritic areas is well known, while their occurrence in the deep sea realm has seldom been considered. Recent investigations showed strict interactions between neritic and deep sea domains, due to up- and down-welling ...
Luigi della Tommasa   +3 more
doaj   +1 more source

In Situ CO2‐Induced Hydrogels for Enhancing Carbon Sequestration in Saline Aquifers

open access: yesAdvanced Science, EarlyView.
A novel integrated method that combines in situ CO2‐induced phase‐transition hydrogels formed by a C22‐tailed tertiary amine dispersion with tailored deep eutectic solvents to increase CO2 sequestration in saline aquifers. ABSTRACT Carbon sequestration in saline aquifers underpins global net‑zero emission goals, yet existing CO2 storage capacity ...
Fuchuan Liu   +5 more
wiley   +1 more source

Resting-state functional connectivity matrices

open access: yes, 2015
Resting-state functional connectivity matrices, in MATLAB data format (.mat)
Danielle S. Bassett (215337)   +7 more
core   +1 more source

Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice

open access: yesAdvanced Science, EarlyView.
CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu   +8 more
wiley   +1 more source

Cyst wall formation in the ciliated protozoan Colpoda cucullus: cyst wall is not originated from pellicle membranes [PDF]

open access: yesInvertebrate Survival Journal, 2006
Ultrastructural changes during encystment (resting cyst formation) of Colpoda cucullus were observed with special reference to cyst wall formation. Within 1.5 h after encystment induction, fragmentation of some of the mitochondria occurred, followed by ...
A Kida, T Matsuoka
doaj   +2 more sources

Relationship between vegetative cells and cyst production during Alexandrium minutum bloom in Arenys de Mar harbour (NW Mediterranean)

open access: yes, 2016
9 pages, 5 figures, 1 tableA recurrent Alexandrium minutum bloom in the Arenys de Mar harbour (Catalan coast, North Western Mediterranean) was monitored in order to establish the relationship between vegetative cells and cyst production. The bloom lasted
Bravo, Isabel   +5 more
core   +1 more source

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