Results 111 to 120 of about 285,581 (295)
Advanced Science, EarlyView.This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu +5 more
wiley +1 more source
Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits
Advanced Science, EarlyView.This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou +3 more
wiley +1 more source
Which is the real resting cyst of Cochlodinium polykrikoides Margalef (Gymnodiniales, Dinophyceae)
, 2014 The ichthyotoxic dinoflagellate Cochlodinium polykrikoides Margalef is the most notorious causative species of dense blooms that have occurred annually in Korean coastal waters.
신현호, 이준, 한명수, 정승원
core
Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology
Advanced Science, EarlyView.Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen +12 more
wiley +1 more source
, 2007 Cyst forming dinoflagellates are useful in reconstructing past environments. For accuracy it is essential to know how environmental parameters such as salinity, temperature and light influence dinoflagellate cyst production and morphology.
Susek, Ewa +3 more
core +1 more source
Advanced Science, EarlyView.During NETosis, neutrophils shift metabolically toward enhanced OXPHOS and partially reduced glycolysis. This shift is driven by PDHA1 hyperactivity‐dependent selective metabolic reprogramming. The neutrophil‐targeted nanoparticle 3‑FP‑BSA NPs effectively inhibit NETosis and attenuate ALI.
Yu‐Biao Liu +14 more
wiley +1 more source
Supramolecular Assembly of an Antimicrobial Peptide Into a Pore
Angewandte Chemie, EarlyView.Supramolecular assembly of an AMP is linked to transport across the Staphylococcus aureus membrane. ABSTRACT Antimicrobial peptides (AMPs) have long been ascribed the ability to form pores. These structures, some observed, others inferred, vary in their mechanisms of action, though most are associated with lysis.
Kathyana Deeyagahage +3 more
wiley +2 more sources
A Rare Complication After Renal Cyst Aspiration: Distal Catheter Fragment Remaining Within the Cyst Wall and Laparoscopic Treatment [PDF]
Simple renal cysts are the most common renal lesions. Percutaneous renal cyst aspiration is an effective and minimally invasive treatment option for symptomatic lesions. This study aims to present the laparoscopic management of the catheter fragment that
Mirsad Yalçınkaya +4 more
core +1 more source
Advanced Science, EarlyView.This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun +12 more
wiley +1 more source
Magnetic Resonance Reveals Radical Stability in Native Biofilms and Its Role in Bacterial Resistance
Angewandte Chemie, EarlyView.The complex biofilm environment consists of planktonic bacterial cells and cells embedded in an extracellular matrix (ECM). Through an integrated magnetic resonance approach, we show that nitroxide radicals primarily interact with the polysaccharides and lipids in the ECM.
Alysia Mandato +10 more
wiley +2 more sources