Results 51 to 60 of about 267,373 (297)
Ожирение и метаболизм, 2019 BACKGROUND: A prerequisite for planning a diet for weight loss in obese children is to determine the level of resting metabolic rate (RMR). The gold standard for estimating the daily energy consumption of rest is indirect respiratory calorimetry. However,
Pavel L. Okorokov +2 more
doaj +1 more source
Cross-Validation of Resting Metabolic Rate Prediction Equations [PDF]
Journal of the Academy of Nutrition and Dietetics, 2016 Resting metabolic rate (RMR) measurement is time consuming and requires specialized equipment. Prediction equations provide an easy method to estimate RMR; however, their accuracy likely varies across individuals. Understanding the factors that influence the accuracy of RMR predictions will help to revise existing, or develop new and improved ...
Kyle D, Flack +3 more
openaire +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Reproducibility of resting metabolic rate measurement in children [PDF]
British Journal of Nutrition, 1999 The aim of the present study was to determine the reproducibility of measurement of resting metabolic rate (RMR) using a ventilated-hood indirect calorimeter in children using a short protocol suitable for the outpatient setting or home visit. The protocol consisted of an overnight (10–12 h) fast, 5–10 min supine rest, 5–10 min ‘settling in’ under the ...
J C, Ventham, J J, Reilly
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Impact of the Metabolic Syndrome and Its Components on Resting Energy Expenditure
Metabolites, 2022 We determined whether metabolic syndrome (MetS) and the increasing number of its components influenced the resting energy expenditure (REE). Data on adult men (n = 72, 40%) and women (n = 108, 60%) from European (n = 154, 86%) and Sub-Saharan African (n =
Mario Soares +6 more
doaj +1 more source
The Effects and Differences of Sprint Interval Training, Endurance Training and the Training Types Combined on Physiological Parameters and Exercise Performance [PDF]
, 2014 Sprint Interval Training (SIT) is a time efficient way in order to elicit similar changes as Endurance Training (ET) on aerobic capacity, with the purpose of the exercise training to alter physiological systems and exceed resting homeostasis to improve ...
Hurst, Rachel Ann
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Seasonal temperature acclimatization in a semi-fossorial mammal and the role of burrows as thermal refuges. [PDF]
, 2018 Small mammals in habitats with strong seasonal variation in the thermal environment often exhibit physiological and behavioral adaptations for coping with thermal extremes and reducing thermoregulatory costs.
Camp, Meghan J +7 more
core +3 more sources
Resting metabolic rate in obese, premenopausal black women [PDF]
The American Journal of Clinical Nutrition, 1997 In the United States, obesity is more prevalent in black than in non-Hispanic white women. Because low resting metabolic rate (RMR) has been suggested as a risk factor for weight gain, we compared RMR in 22 black and 20 white obese [body mass index (BMI; in kg/m2) range: 28.9-48.6 and 26.9-44.1, respectively], weight-stable, premenopausal, nondiabetic ...
J, Albu +5 more
openaire +2 more sources